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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.9
- 수록면
- 280 - 283 (4page)
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초록· 키워드
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Leuconostoc spp. is intrinsically resistant against vancomycin and rarely causes the infection in immunocompromised patients. In this report, we describe a fatal case of Leuconostoc lactis bacteremia in a patient with biliary tract stent insertion to resolve the biliary tract obstruction by multiple pseudocysts in the pancreatic head region. Leuconostic lactis isolated from the blood of the patients was confirmed by 16S rRNA sequencing and this isolate was susceptible against most antibiotics, including levofloxacin, penicillin, erythromycin and cefotaxime except vancomycin. The septic shock and multi-organ failure was abruptly progressed due to delayed use of adequate antibiotic. Using vancomycin as the empirical antibiotics in a bacteremic patient by Gram positive cocci, the treatment failures by the isolates with intrinsic resistance against vancomycin have to be considered. In addition, the prompt and accurate identification of Leuconostoc spp. are very important to select the adequate antibiotics.
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REFERENCES
참고문헌 (23)
참고문헌 신청
Aguirre M / 1993 / Lactic acid bacteria and human infection / J Appl Bacteriol 75:95~107
Cibik R / 2000 / Molecular diversity of Leuconostoc mesenteroides and Leuconostoc citreum isolated from traditional French cheeses as revealed by RAPD fingerprinting, 16S rDNA sequencing and 16S rDNA fragment amplification / Syst Appl Microbiol 23:267~278
Coovaida YM / 1987 / Meningitis caused by vancomycin-resistant Leuconostoc sp / J Clin Microbiol 25:1784~1785
Facklam R / 1995 / Identification, classification, and clinical relevance of catalase-negative, Gram-positive cocci, excluding the streptococci and enterococci / Clin Microbiol Rev 8:479~495
Freifeld AG / 2011 / Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Disease Society of America / Clin Infect Dis 52:e56~e93
Cibik R / 2000 / Molecular diversity of Leuconostoc mesenteroides and Leuconostoc citreum isolated from traditional French cheeses as revealed by RAPD fingerprinting, 16S rDNA sequencing and 16S rDNA fragment amplification / Syst Appl Microbiol 23:267~278
Coovaida YM / 1987 / Meningitis caused by vancomycin-resistant Leuconostoc sp / J Clin Microbiol 25:1784~1785
Facklam R / 1995 / Identification, classification, and clinical relevance of catalase-negative, Gram-positive cocci, excluding the streptococci and enterococci / Clin Microbiol Rev 8:479~495
Freifeld AG / 2011 / Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Disease Society of America / Clin Infect Dis 52:e56~e93
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UCI(KEPA) : I410-ECN-0101-2014-500-002674024