Purpose: The purpose of the study was to discover long-term effects of Problem-based learning (PBL) and Simulation Problem-based learning (S-PBL) on critical thinking, problem solving abilities, learning attitude, motivation, and learning satisfaction among nursing students at Cheju Halla College. These students were taking problem based learning and simulation as a problem based learning method with an integrated curriculum. Methods: This study used a pretest-posttest with repeated measure design. Data was collected using convenience sampling from the beginning of the 1st semester to the end of the 2nd year when the PBL and S-PBL were completed by those who were enrolled in the integrated nursing curriculum. One-hundred eighty-three surveys were collected and analyzed during the repeat data collection. Results: There we restatistically significant differences of critical thinking, problem solving abilities, learning attitude, motivation and satisfaction post PBL and S-PBL. Conclusion: This study contributes to our understanding of outcomes from the PBL and S-PBL approach. The students undertaking PBL and S-PBL demonstrated that they developed a more positive attitude about their educational experience. In addition, students’ tendency to think critically and problem solve improved through the use of the PBL and S-PBL approach.