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논문 기본 정보

자료유형
학술저널
저자정보
Dongmin Lee (Chungbuk National University School of Medicine) Seongjun Choe (Chungbuk National University School of Medicine) Hansol Park (Chungbuk National University School of Medicine) Hyeong-Kyu Jeon (Chungbuk National University School of Medicine) Jong-Yil Chai (Seoul National University College of Medicine) Woon-Mok Sohn (Gyeongsang National University School of Medicine) Tai-Soon Yong (Yonsei University College of Medicine) Duk-Young Min (Eulji University School of Medicine) Han-Jong Rim (Korea University College of Medicine) Keeseon S. Eom (Chungbuk National University School of Medicine)
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.51 No.6
발행연도
2013.12
수록면
719 - 726 (8page)

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Mitochondrial genomes have been extensively studied for phylogenetic purposes and to investigate intra- and interspecific genetic variations. In recent years, numerous groups have undertaken sequencing of platyhelminth mitochondrial genomes. Haplorchis taichui (family Heterophyidae) is a trematode that infects humans and animals mainly in Asia, including the Mekong River basin. We sequenced and determined the organization of the complete mitochondrial genome of H. taichui. The mitochondrial genome is 15,130 bp long, containing 12 protein-coding genes, 2 ribosomal RNAs (rRNAs, a small and a large subunit), and 22 transfer RNAs (tRNAs). Like other trematodes, it does not encode the atp8 gene. All genes are transcribed from the same strand. The ATG initiation codon is used for 9 protein-coding genes, and GTG for the remaining 3 (nad1, nad4, and nad5). The mitochondrial genome of H. taichui has a single long non-coding region between trnE and trnG. H. taichui has evolved as being more closely related to Opisthorchiidae than other trematode groups with maximal support in the phylogenetic analysis. Our results could provide a resource for the comparative mitochondrial genome analysis of trematodes, and may yield genetic markers for molecular epidemiological investigations into intestinal flukes.

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Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES

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