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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 155 - 160 (6page)
이용수
초록· 키워드
오류제보하기
Purpose: It has been reported that xylitol and sorbitol affect antifungal activities by enhancing antimicrobial activities of other substances. The purpose of this study was to investigate the direct candidacidal activities of xylitol and sorbitol at a wide range of concentration.
Methods: Xylitol and sorbitol solubilized with simulated salivary buffer at a range of 0.8 μM to 1.05 M were used. Candida albicans strains, ATCC strains 10231, 11006, and 18804 were used for the candidacidal assay. The candidacidal activities of xylitol and sorbitol were determined by comparing the numbers of colony forming units between in the presence and absence of xylitol or sorbitol and calculating the percent loss of cell viability.
Results: There were some differences in the candidacidal activities according to the types of sugar alcohols and C. albicans strains. The candidacidal activity of more than 10% was observed when a final concentration of 32.9 mM in xylitol or sorbitol was maintained and that of about 20% was observed when a final concentration of 131 mM was maintained. Even at a high concentration of 1.05 M, the candidacidal activity of xylitol or sorbitol was about 20%.
Conclusions: Xylitol and sorbitol at the concentrations used in commercial oral health care products had some levels of candidacidal activities.
Methods: Xylitol and sorbitol solubilized with simulated salivary buffer at a range of 0.8 μM to 1.05 M were used. Candida albicans strains, ATCC strains 10231, 11006, and 18804 were used for the candidacidal assay. The candidacidal activities of xylitol and sorbitol were determined by comparing the numbers of colony forming units between in the presence and absence of xylitol or sorbitol and calculating the percent loss of cell viability.
Results: There were some differences in the candidacidal activities according to the types of sugar alcohols and C. albicans strains. The candidacidal activity of more than 10% was observed when a final concentration of 32.9 mM in xylitol or sorbitol was maintained and that of about 20% was observed when a final concentration of 131 mM was maintained. Even at a high concentration of 1.05 M, the candidacidal activity of xylitol or sorbitol was about 20%.
Conclusions: Xylitol and sorbitol at the concentrations used in commercial oral health care products had some levels of candidacidal activities.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (22)
참고문헌 신청
[학술지(정기간행물)] - Söderling EM / 2009 / Xylitol, mutans streptococci, and dental plaque / Adv Dent Res 21 : 74 ~ 78
[학술지(정기간행물)] - Gales MA / 2000 / Sorbitol compared with xylitol in prevention of dental caries / Ann Pharmacother 34 : 98 ~ 100
[학술지(정기간행물)] - Van Loveren C / 2004 / Sugar alcohols: what is the evidence for cariespreventive and caries-therapeutic effects? / Caries Res 38 : 286 ~ 293
[학술지(정기간행물)] - Ur-Rehman S / 2015 / Xylitol:a review on bioproduction, application, health benefits, and related safety issues / Crit Rev Food Sci Nutr 55 : 1514 ~ 1528
[학술지(정기간행물)] - Paula VA / 2010 / Antimicrobial effects of the combination of chlorhexidine and xylitol / Br Dent J 209 : E19 ~
[학술지(정기간행물)] - Gales MA / 2000 / Sorbitol compared with xylitol in prevention of dental caries / Ann Pharmacother 34 : 98 ~ 100
[학술지(정기간행물)] - Van Loveren C / 2004 / Sugar alcohols: what is the evidence for cariespreventive and caries-therapeutic effects? / Caries Res 38 : 286 ~ 293
[학술지(정기간행물)] - Ur-Rehman S / 2015 / Xylitol:a review on bioproduction, application, health benefits, and related safety issues / Crit Rev Food Sci Nutr 55 : 1514 ~ 1528
[학술지(정기간행물)] - Paula VA / 2010 / Antimicrobial effects of the combination of chlorhexidine and xylitol / Br Dent J 209 : E19 ~
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UCI(KEPA) : I410-ECN-0101-2017-515-002046525