지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 199 - 206 (8page)
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초록· 키워드
오류제보하기
Pesticides are widely used to prevent loss of agricultural production but extensive exposure can induce health problems to pesticide operators. This study was performed to evaluate the health risk of highly produced pesticides used in fruit growing farm land by comparison of estimated exposure level with AOEL using KO-POEM program. AOEL was driven based on NOAEL of each pesticide evaluated by JMPR, EFSA or KRDA. In calculation of exposure level, types of formulation, dilution factors, spraying duration and motor type and exposure protection device were allocated according to actual condition of use. Dermal absorption rate was differently applied among EFSA default values (25% or 75%), general default value (10%) or real test result values to know the plausibility of default values and safety of pesticide to operators in outline. Twenty pesticide ingredients (fungicides and insecticides) were produced more than 30 tons per year, which were mancozeb, chlorothalonil, imidaclopirid and etc in order. Dermal absorption rates obtained from studies were various from 0.07 to 81% but mostly under 10%. The estimated exposure levels showed big differences more than 10 times higher when using EFSA default rate and up to 5 times higher when using general rate of 10% comparing using rates of test results. Mancozeb, chlorthalonil, diazinon and chlorpyrifos presented still higher exposure level than AOEL even when using test absorption rate from study, which suggests that re-evaluation of AOEL or dermal exposure absorption rate or strict management are required for health protection of operators who use those four pesticides in farm land.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (27)
참고문헌 신청
Aggarwal M / 2015 / Assessment of an extended dataset of in vitro human dermal absorption studies on pesticides to determine default values, opportunities for read-across and influence of dilution on absorption / Regul Toxicol Pharmacol 72:58~70
California Environment Protection Agency / 2005 / Chlorothalonil risk chracterization document for dietary exposure
California Department of Food and Agriculture Worker Health and Safety Branch / 1988 / Human Exposure Assessment Myclobutanil
최훈 / 2014 / 고추, 오이 및 사과 재배 중 살균제 Thiophanate-methyl 살포 시농작업자의 노출 및 위해 평가 / Journal of Applied Biological Chemistry 57(1):73~81
CTGB Netherlands / 2016 / Registration report part A risk management dithianon
California Environment Protection Agency / 2005 / Chlorothalonil risk chracterization document for dietary exposure
California Department of Food and Agriculture Worker Health and Safety Branch / 1988 / Human Exposure Assessment Myclobutanil
최훈 / 2014 / 고추, 오이 및 사과 재배 중 살균제 Thiophanate-methyl 살포 시농작업자의 노출 및 위해 평가 / Journal of Applied Biological Chemistry 57(1):73~81
CTGB Netherlands / 2016 / Registration report part A risk management dithianon
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UCI(KEPA) : I410-ECN-0101-2017-510-002026413