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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.4
- 수록면
- 244 - 249 (6page)
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초록· 키워드
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The inhibitory effects of adipogenesis in 3T3-L1 adipocytes with water and ethanol extracts of Curdrania tricuspidata leaves were investigated. The lipid accumulation of ethanol extract from Curdrania tricuspidata leaves at a concentration of 5 mg/mL was reduced by 50% compared with control cells, whereas water extracts reduced by 86%. The survival rate of cell viability test showed 80% in the growth of cells at concentrations of 0.5-5 mg/mL. The contents of DNJ(1-deoxynojirimycin) and rutin were higher in leaves than those of stem. Moreover, DNJ contents were detected in large amounts in ethanol extract (3921.3 μg/g) compared with water extract (2906.3 μg/g). On the contrary, the rutin contents was detected in large amounts in water extracts compared with ethanol extract. These results indicate that Curdrania tricuspidata leaves extract is potential sources of natural antiobesity agent.
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참고문헌 (20)
참고문헌 신청
1. [학술지(정기간행물)] - Kopelman PG / 2000 / Obesity as a medical problem / Nature 404 : 635 ~ 643
2. [학술지(정기간행물)] - Green H / 1974 / Sublines of mouse 3T3 cells that accumlate lipid / Cell 1 : 113 ~ 116
3. [학술지(정기간행물)] - Otto TC / 2005 / Adipose development from stem cell to adipocyte / Crit Rev Biochem Mol Biol 40 : 229 ~ 242
4. [학술지(정기간행물)] - Kim SH / 1993 / Determination of flavonoid by HPLC and biological activities from the leaves of Cudrania tricuspidata Bureau / J Korean Soc Food Sci Nutr 22 : 68 ~ 72
5. [학술지(정기간행물)] - Otlersen T / 1977 / The crystal structure of cudranone, 2,6,3'-trihydroxy-4-methoxy-2'-(3-methoxy-2-buternyl)-I, a new antimicrobial agent from Cudrania chochinchinensis / Acta Chem Scand 31 : 434 ~ 436
2. [학술지(정기간행물)] - Green H / 1974 / Sublines of mouse 3T3 cells that accumlate lipid / Cell 1 : 113 ~ 116
3. [학술지(정기간행물)] - Otto TC / 2005 / Adipose development from stem cell to adipocyte / Crit Rev Biochem Mol Biol 40 : 229 ~ 242
4. [학술지(정기간행물)] - Kim SH / 1993 / Determination of flavonoid by HPLC and biological activities from the leaves of Cudrania tricuspidata Bureau / J Korean Soc Food Sci Nutr 22 : 68 ~ 72
5. [학술지(정기간행물)] - Otlersen T / 1977 / The crystal structure of cudranone, 2,6,3'-trihydroxy-4-methoxy-2'-(3-methoxy-2-buternyl)-I, a new antimicrobial agent from Cudrania chochinchinensis / Acta Chem Scand 31 : 434 ~ 436
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