지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background and Purpose Perfusion-diffusion mismatch has been evaluated to determine whether the presence of a target mismatch helps to identify patients who respond favorably to recanalization therapies. We compared the impact on infarct growth of collateral status and the presence of a penumbra, using magnetic resonance perfusion (MRP) techniques.
Methods Consecutive patients who were candidates for recanalization therapy and underwent serial diffusion-weighted imaging (DWI) and MRP were enrolled. A collateral flow map derived from MRP source data was generated by automatic post-processing. The impact of a target mismatch (Tmax>6 s/apparent diffusion coefficient (ADC) volume≥1.8, ADC volume<70 mL; and Tmax>10 s for ADC volume<100 mL) on infarct growth was compared with MR-based collateral grading on day 7 DWI, using multivariate linear regression analysis.
Results Among 73 patients, 55 (75%) showed a target mismatch, whereas collaterals were poor in 14 (19.2%), intermediate in 36 (49.3%), and good in 23 (31.5%) patients. After adjusting for initial severity of stroke, early recanalization (P<0.001) and the MR-based collateral grading (P=0.001), but not the presence of a target mismatch, were independently associated with infarct growth. Even in patients with a target mismatch and successful recanalization, the degree of infarct growth depended on the collateral status. Perfusion status at later Tmax time points (beyond the arterial phase) was more closely correlated with collateral status.
Conclusions Patients with good collaterals show a favorable outcome in terms of infarct growth, regardless of the presence of a target mismatch pattern. The presence of slow blood filling predicts collateral status and infarct growth.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Bang O / 2008 / Determinants of the distribution and severity of hypoperfusion in patients with ischemic stroke / Neurology 71:1804~1811
Lee MJ / 2015 / Predicting collateral status with MR perfusion parameters: probabilistic approach with a Tmax-derived prediction model / Stroke 46:2800~2807
Campbell BC / 2010 / Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke / Stroke 41:82~88
Bang OY / 2015 / Collateral circulation in ischemic stroke: assessment tools and therapeutic strategies / Stroke 46:3302~3309
Adams HP Jr / 1993 / Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treat
Lee MJ / 2015 / Predicting collateral status with MR perfusion parameters: probabilistic approach with a Tmax-derived prediction model / Stroke 46:2800~2807
Campbell BC / 2010 / Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke / Stroke 41:82~88
Bang OY / 2015 / Collateral circulation in ischemic stroke: assessment tools and therapeutic strategies / Stroke 46:3302~3309
Adams HP Jr / 1993 / Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treat
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Impacts of Rapid Recanalization and Collateral Circulation on Clinical Outcome after Intraarterial Thrombolysis
대한뇌졸중학회지
2015 .01
-
CT Angiography of Collateral Vessels and Outcomes in Endovascular-Treated Acute Ischemic Stroke Patients
Journal of Clinical Neurology
2017 .01
-
Selection of Candidates for Endovascular Treatment: Characteristics According to Three Different Selection Methods
대한뇌졸중학회지
2019 .01
-
Outcome Prediction Using Perfusion Parameters and Collateral Scores of Multi-Phase and Single-Phase CT Angiography in Acute Stroke: Need for One, Two, Three, or Thirty Scans?
대한뇌졸중학회지
2018 .01
-
Cerebro-/Cardiovascular Collateral Damage During the COVID-19 Pandemic: Fact or Fiction?
Journal of Clinical Neurology
2023 .01
-
Collateral Circulation in Ischemic Stroke: An Updated Review
대한뇌졸중학회지
2023 .05
-
Combination of High-Density Lipoprotein Cholesterol and Lipoprotein(a) as a Predictor of Collateral Circulation in Patients With Severe Unilateral Internal Carotid Artery Stenosis or Occlusion
Journal of Clinical Neurology
2022 .01
-
Prediction of Early Recanalization after Intravenous Thrombolysis in Patients with Large-Vessel Occlusion
대한뇌졸중학회지
2021 .01
-
Correlation between Serum Erythropoietin and Cerebral Collateral Flow in Acute Ischemic Stroke Patient
Korean Journal of Family Medicine
2023 .01
-
Perfusion and Diffusion Variables Predict Early Neurological Deterioration in Minor Stroke and Large Vessel Occlusion
대한뇌졸중학회지
2021 .01
-
COVID-19에 의한 EMS 동반손상
한국응급구조학회지
2021 .12
-
Comparison of Ulnar Collateral Ligament Reconstruction Techniques in the Elbow of Sports Players
대한견주관절의학회지
2020 .03
-
Extending the stroke treatment window beyond DAWN in patients with very slow progressor type collaterals: How far can we go?
Journal of Cerebrovascular and Endovascular Neurosurgery
2021 .12
-
Quantitative Magnetic Resonance Angiography in Internal Carotid Artery Occlusion with Primary Collateral Pathway
대한뇌졸중학회지
2015 .01
-
Management of Ulnar Collateral Ligament Injuries in Overhead Athletes
대한견주관절의학회지
2019 .12
-
Arthroscopic lateral ulnar collateral ligament repair
대한견주관절의학회 학술대회논문집
2015 .04
-
Portosystemic collateral pathways and interventions in portal hypertension
International Journal of Gastrointestinal Intervention
2018 .01
-
Blood Pressure May Be Associated with Arterial Collateralization in Anterior Circulation Ischemic Stroke before Acute Reperfusion Therapy
대한뇌졸중학회지
2017 .01
-
Efficacy and Safety of Endovascular Treatment in Patients with Internal Carotid Artery Occlusion and Collateral Middle Cerebral Artery Flow
대한신경외과학회지
2019 .01
-
The Existence and Distribution of Mechanoreceptors of Elbow’s Medial Collateral Ligament
대한견주관절의학회 학술대회논문집
2017 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0