지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제23권 제3호
- 발행연도
- 2018.1
- 수록면
- 148 - 153 (6page)
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초록· 키워드
오류제보하기
Purpose: To analyze the effects of clinical and laboratory factors, including insulinlike growth factor (IGF) levels, on the height velocity of normal prepubertal children. Methods: Ninety-five healthy prepubertal children (33 boys, 62 girls) were enrolled. The mean chronological age was 6.3±1.4 years, with a height standard deviation score (SDS) of -0.88±0.70. IGF-1, IGF binding protein-3 (IGFBP-3), SDS for anthropometric measurements, and changes in SDS for anthropometric measurements were analyzed for 1 year, and their associations with 1-year height velocity were investigated. Results: The group of children with a 1-year height velocity of ≥6 cm were chronologically younger than the group with a 1-year height velocity of <6 cm (5.9±1.3 years vs. 6.7±1.3 years, P=0.004), with a lesser increase of SDS for body mass index (BMI) over 1 year (-0.18±0.68 vs. 0.13±0.53, P=0.014). There were no differences between the 2 groups in IGF-1 SDS and IGFBP-3 SDS. Multiple linear regression showed that baseline chronological age (r=0.243, P=0.026) and height SDS (r=0.236, P=0.030) were positively associated with IGF-1 SDS. Binomial logistic regression showed that an older chronologic age at referral (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.47–0.99) and an increase of BMI SDS over 1 year (OR, 0.41; 95% CI, 0.18–0.89) were associated with a decreased growth possibility of an above-average height velocity (≥6 cm/yr). Conclusion: Height velocity of normal prepubertal children is affected by an increase of BMI SDS and chronological age. Prepubertal IGF-1 SDS reflects height SDS at the time of measurement but is not associated with subsequent height velocity.
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참고문헌 (31)
참고문헌 신청
Himes JH / 1985 / Parentspecific adjustments for evaluation of recumbent length and stature of children / Pediatrics 75:304~313
WHO Multicentre Growth Reference Study Group / 2006 / WHO Child Growth Standards based on length/height, weight and age / Acta Paediatr Suppl 450:76~85
Stenhouse E / 2004 / The accuracy of birth weight / J Clin Nurs 13:767~768
Gluckman PD / 2011 / Losing the war against obesity: the need for a developmental perspective / Sci Transl Med 3:93
Dewey KG / 1995 / Growth of breast-fed infants deviates from current reference data: a pooled analysis of US, Canadian, and European data sets. World Health Organization Working Group on Infant Growth / Pediatrics 96(3):495~503
WHO Multicentre Growth Reference Study Group / 2006 / WHO Child Growth Standards based on length/height, weight and age / Acta Paediatr Suppl 450:76~85
Stenhouse E / 2004 / The accuracy of birth weight / J Clin Nurs 13:767~768
Gluckman PD / 2011 / Losing the war against obesity: the need for a developmental perspective / Sci Transl Med 3:93
Dewey KG / 1995 / Growth of breast-fed infants deviates from current reference data: a pooled analysis of US, Canadian, and European data sets. World Health Organization Working Group on Infant Growth / Pediatrics 96(3):495~503
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