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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제19권 제3호
- 발행연도
- 2016.1
- 수록면
- 210 - 213 (4page)
이용수
초록· 키워드
오류제보하기
Primary sclerosing cholangitis (PSC), a rare progressive liver disease characterized by cholestasis and bile duct fibrosis, has no accepted, effective therapy known to delay or arrest its progression. We report a 15 year old female patient diagnosed with PSC and moderate chronic active ulcerative colitis (UC) who achieved normalization of her liver enzymes and bile ducts, and resolution of her UC symptoms with colonic mucosal healing, after treatment with a single drug therapy of the antibiotic oral vancomycin. We postulate that the oral vancomycin may be acting both as an antibiotic by altering the intestinal microbiome and as an immunomodulator. Oral vancomycin may be a promis-ing treatment for PSC that needs to be further studied in randomized trials.
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등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Tabibian JH / 2014 / Primary sclerosing cholangitis and the microbiota: current knowledge and perspectives on etiopathogenesis and emerging therapies / Scand J Gastroenterol 49:901~908
Björnsson E / 2008 / The natural history of small-duct primary sclerosing cholangitis / Gastroenterology 134:975~980
Lindor KD / 2015 / American College of Gastroenterology. ACG clinical guideline: primary sclerosing cholangitis / Am J Gastroenterol 110:646~659
Miloh T / 2009 / A retrospective single-center review of primary sclerosing cholangitis in children / Clin Gastroenterol Hepatol 7:239~245
Feldstein AE / 2003 / Primary sclerosing cholangitis in children: a long-term follow-up study / Hepatology 38:210~217
Björnsson E / 2008 / The natural history of small-duct primary sclerosing cholangitis / Gastroenterology 134:975~980
Lindor KD / 2015 / American College of Gastroenterology. ACG clinical guideline: primary sclerosing cholangitis / Am J Gastroenterol 110:646~659
Miloh T / 2009 / A retrospective single-center review of primary sclerosing cholangitis in children / Clin Gastroenterol Hepatol 7:239~245
Feldstein AE / 2003 / Primary sclerosing cholangitis in children: a long-term follow-up study / Hepatology 38:210~217
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