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논문 기본 정보

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학술저널
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대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제3권 제4호
발행연도
2015.1
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272 - 280 (9page)

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Purpose: We investigated the prevalence and risk factors of allergic rhinitis (AR), nationwide in random children and adolescents of Korea. Methods: A modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire survey was done in 1,820 children from elementary, middle, and high school nationwide in Korea. The subjects were selected by the stratifying sampling method by school grade and five regions. Current AR was defined as having AR symptoms during the last 12 months with a history of physician-diagnosed AR. Skin prick tests for 18 common allergens were performed. Results: The number of males was 945, and that of females was 875. The mean age of the patients was 12.61±3.40 years. The prevalence of current AR and atopic current AR were 29.0% and 18.7%, respectively. Risk factors for current AR were male (adjusted odds ratio [aOR], 1.486; 95% confidence interval [CI], 1.189–1.856), family history of paternal AR (aOR, 3.208; 95% CI, 2.460–4.182), family history of maternal AR (aOR, 3.138; 95% CI, 2.446–4.025), antibiotic use in infancy (aOR, 1.547; 95% CI, 1.228–1.949), mold exposure during infancy (aOR, 1.416; 95% CI, 1.103–1.819), mold exposure during the last 12 months (aOR, 1.285; 95% CI, 1.012–1.630), and sensitization on skin prick tests (aOR, 2.596; 95% CI, 2.055–3.279). Risk factors for atopic current AR were the same as those of current AR, whereas breast-milk feeding (aOR, 0.720; 95% CI, 0.530–0.976) was a protective factor. Sensitized allergens as risk factors for current AR were Dermatophagoides pteronyssinus, Dermatophagoides farina, ragweed, mugwort, oak, alder, birch, Japanese hop, cat, and dog. Conclusion: The prevalences of current AR and atopic current AR were 29.0% and 18.7%, respectively. Male, sex parental AR, antibiotic use in infancy, mold exposure during the last 12 months, mold exposure during infancy, and atopic sensitization were risk factors for current AR. Breast-milk feeding was a protective factor for atopic current AR. Aeroallergen sensitization was an important risk factor for AR.
#Allergic rhinitis #Prevalence #Risk factors #Sensitization #Child

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참고문헌 (24)

참고문헌 신청
Bjorksten B / 1999 / The intestinal microflora in allergic Estonian and Swedish 2-year-old children / Clin Exp Allergy 29 : 342 ~ 346 google schola Bousquet J / 2008 / Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen) / Allergy 86 (S google schola Foliaki S / 2009 / Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: international study of asthma and allergi google schola Ha M / 2014 / Korean Environmental Health Survey in Children and Adolescents(KorEHS-C) : survey design and pilot study results on selected exposure biomarkers / Int J Hyg En google schola Hoskin-Parr L / 2013 / Antibiotic exposure in the first two years of life and development of asthma and other allergic diseases by 7.5 yr: a dose-dependent relationship / Pe google schola

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