레이저 성대 절제술을 시행한 조기 성문암 환자의 치료 결과 및  전암성 병변으로 부터의 악성 변환 관찰

안동빈; 박지현; 허성재; 박창묵; 정다정; 남예모; 손진호; 박준식

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자료유형: 학술저널

저자정보: 안동빈 박지현 허성재 박창묵 정다정 남예모 손진호 박준식

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제53권 제7호

발행연도: 2010.1

수록면: 425 - 429 (5page)

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연구결과

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Background and Objectives Laser cordectomy has been widely acknowledged to have advantages for the treatment of early glottic carcinoma. This study was performed to assess the results of laser cordectomy for its oncologic safeness, time-effectiveness, and to report a few interesting precancerous cases that have progressed to glottic cancer. Subjects and Method Subjects (47) who had undergone laser cordectomy for the treatment of early glottic cancer from April 2006 to July 2009 were enrolled in this study. We analyzed the oncologic outcomes, the duration of hospital treatment after the surgery, and postoperative complications by reviewing of medical records. Results For 47 cases, the mean age was 66 years and the mean follow up period was 22.6months. The mean duration of treatment was 1.9 days. Among them, 24 cases were classified into T1a, 12 T1b, and 2 T2. Local recurrence was observed in 2 cases, so salvage treatments, such as radiation therapy or near total laryngectomy, were performed, and both of them were alive in the disease-free state. The most common complication was anterior commissure web, which was observed in 6 cases (15.8%), followed by granuloma observed in 5 cases (13.1%). Serious complications such as aspiration, respiratory distress, and dysphagia were not found in any of 47 cases. Also, we could observe 3 cases in which the precancerous glottic lesion had progressed to glottic carcinoma over a long period of time. Conclusion Laser cordectomy might be the treatment of choice for patient’s convenience because of its excellent oncologic outcomes, low morbidity, and time-effectiveness. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:425-9

#Glottis·Carcinoma·Laser surgery·Precancerous condition.

참고문헌 (20)

참고문헌 신청

Cragle SP / 1993 / Laser cordectomy or radiotherapy: cure rates, communication, and cost / Otolaryngol Head Neck Surg 108 (6) : 648 ~ 654

Department of otorhinolaryngology / 2007 / Seoul national university college of medicine. Laser surgery for laryngeal cancer / Seoul symposium : 174 ~ 186

Friedmann I / 1986 / Nose, throat and ears. 3rd ed / Churchill Livingstone

Gallo A / 2002 / CO2 Laser cordectomy for early-stage glottis carcinoma: a long-term follow up of 156 cases / Laryngoscope 112 (2) : 370 ~ 374

Mendenhall WM / 1994 / Management of Tis, T1 and T2 squamous carcinoma of the glottic larynx / Am J Otolaryngol 15 (4) : 250 ~ 257

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