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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 617 - 622 (6page)
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초록· 키워드
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Nanoencapsulation is the coating of various substances within another material at sizes on the nanoscales and it is prospected in all kinds of industries especially cosmetics, pharmaceutics, and food manufacturing.
This study was performed to investigate the antioxidant activities as comparing ethanol extracts (ME) and nano-encapsulation of Mulberry Root Bark Extracts by lecithin and cholesterol (NM). DPPH radical scavenging activity of both extracts are almost identical for the 250 ug/ml samples. Also, the effects on nano-encapsulated extracts (NM) and ethanol extracts (ME) on the generation (induction) of Reactive Oxygen Species (ROS)by adding LPS to induce oxygen stress into the cell was that the both extracts in adding sample (500 ㎍/㎖)or (1000 ㎍/㎖) showed similar to oxidative stresses inhibition compared to 50% of control. ln addition, cell viability of the nano-encapsulated extracts (NM) was measured on RAW 264.7 cells and showed higher than that of ethanol extract (ME) in each concentration. The size of the nano-encapsulated extracts (NM) was an average diameter of range of 200-400 nm so they can effectively penetrate cell more than ethanol extract (ME)as nano-encapsulated extracts (NM) have great mobility and affinity for cell because of their small size. it was observed by confocal laser scanning microscope.
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참고문헌 (32)
참고문헌 신청
Ames BN / 1989 / Endogenous DNA damage as related to cancer and aging Mutat / Res 214 : 41 ~ 46
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181 : 1199 ~ 2000
Chun-Whan Choi / 2007 / Antioxidant Constituents and a New Triterpenoid Glycoside from Flos Lonicerae / Archives of Pharmacal Research 30 (1) : 1 ~ 7
Freeman BA / 1982 / Biology of disease; free radicals and tissue injury / Laboratory Investigation 47 : 412 ~ 426
Hikino H / 1985 / Isolation and Hypoglycemic activity of Moran A a glycoprotein of Morus alba root barks / Planta Medica 51 : 159 ~ 163
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181 : 1199 ~ 2000
Chun-Whan Choi / 2007 / Antioxidant Constituents and a New Triterpenoid Glycoside from Flos Lonicerae / Archives of Pharmacal Research 30 (1) : 1 ~ 7
Freeman BA / 1982 / Biology of disease; free radicals and tissue injury / Laboratory Investigation 47 : 412 ~ 426
Hikino H / 1985 / Isolation and Hypoglycemic activity of Moran A a glycoprotein of Morus alba root barks / Planta Medica 51 : 159 ~ 163
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