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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 69 - 74 (6page)
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초록· 키워드
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Lactic acid bacteria (LAB) were well known to enhance the intestinal health of human. For the development of pharmaceutical LAB, it was screened that the LAB with activity lowering the cholesterol in vitro and evaluated the hypocholestrolemic effect of live and heat-killed (HK) LAB on rats. The selected Lactobacillus plantarum CBT 1209 and Lactobacillus rhamnosus
CBT 1702 had the deconjugation of bile salts and assimilation of cholesterol micelles activities from laboratory media. The mixture of 1702 and 1209 strains was administrated to the rats with high cholesterol diet. The experiment performed by 4 groups which were control, HCD, LLAB, HKLAB groups. The hypocholesterolemic effect of LAB (strains 1702, 1209) at blood level, the phenomena of AI decreasing through LDL-cholesterol dwindling, was assessed. This effect of 1702 and 1209 was enhanced when it comes to be the HKLAB more the live-LAB. This data means that the Lactobacillus rhamnosus CBT 1702 and Lactobacillus plantarum CBT 1209 were very useful functional ingredient for hypercholesterolemia.
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등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Anderson, J. W / 1999 / Effect of fermented milk (yogurt) containing Lactobacillus acidophilus L1 on serum cholesterol in hypercholesterolemic humans / J. Am. Coll. Nutr 18 (
Brown, M. S / 1995 / Method and composition for identifying substances which activate transcription of the LDL receptor gene / Biotechnology Advances 13 (4) : 724 ~ 725
Creager, M. A / 1990 / Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans / J. Clin. Invest. 86 (1) : 228 ~ 234
Dora / 2002 / Cholesterol assimilation by lactic acid bacteria and bifidobacteria isolated form the human gut. Appl / Environ Microbiology 68 (9) : 4689 ~ 4693
Grundy, S. M / 1965 / Quantitative isolation and gas-liquid chromatographic analysis of total and fecal bile acids / J Lipid Res 6 : 397 ~ 410
Brown, M. S / 1995 / Method and composition for identifying substances which activate transcription of the LDL receptor gene / Biotechnology Advances 13 (4) : 724 ~ 725
Creager, M. A / 1990 / Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans / J. Clin. Invest. 86 (1) : 228 ~ 234
Dora / 2002 / Cholesterol assimilation by lactic acid bacteria and bifidobacteria isolated form the human gut. Appl / Environ Microbiology 68 (9) : 4689 ~ 4693
Grundy, S. M / 1965 / Quantitative isolation and gas-liquid chromatographic analysis of total and fecal bile acids / J Lipid Res 6 : 397 ~ 410
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