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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제28권 제5호
- 발행연도
- 2018.1
- 수록면
- 688 - 696 (9page)
이용수
이 논문의 연구 히스토리 (2)
2018
Anti-Obese Effects of a Mixture of Fermented Ginseng, Bifidobacterium longum BORI, and Lactobacillus paracasei CH88 in High-Fat Diet-Fed Mice
강다영
식품영양학과
2018.01
학위논문
Anti-Obesity Effects of a Mixture of Fermented Ginseng, Bifidobacterium longum BORI, and Lactobacillus paracasei CH88 in High-Fat Diet-Fed Mice
강다영
,
Zhipeng Li
,
지근억
Journal of Microbiology and Biotechnology
2018.01
학술저널
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초록· 키워드
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Ginseng and probiotics have anti-obesity effects in mice fed a high-fat diet (HFD). Absorption of ginsenoside and colonization of probiotics occur in the intestine. In this study, a mixture of fermented ginseng and two probiotics, Bifidobacterium longum BORI and Lactobacillus paracasei CH88, was administered to HFD-fed mice for 9 weeks. The mixture significantly suppressed weight gain (p < 0.05, n = 8) and lipid deposition in the liver and adipose tissues as well as increased the mice’s food intake. The adipocyte size of the adipose tissue was significantly decreased in the mixture-fed group, especially when 0.5% fermented ginseng and 5 × 108/ml of the two probiotics were used (p < 0.05, n = 10). The expression of TNF-α in adipose tissue was efficiently downregulated in the mixture-fed group (p < 0.05, n = 4). The supplement also improved the mice’s fasting blood glucose levels (p < 0.05, n = 8) and total cholesterol feces excretion (p < 0.05, n = 8). The mixture of fermented ginseng and B. longum BORI and L. paracasei CH88 could have an anti-obesity effect and suppress lipid deposit in the liver and adipose tissues.
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등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
Jung S / 2014 / Anti-obesity and anti-inflammatory effects of high hydrostatic pressure extracts of ginseng in high-fat diet induced obese rats / J. Funct. Foods 10:169~177
Ku S / 2016 / Review on Bifidobacterium bifidum BGN4: functionality and nutraceutical applications as a probiotic microorganism / Int. J. Mol. Sci. 17:E1544
Shen J / 2012 / The gut microbiota, obesity and insulin resistance / Mol. Aspects Med. 34:39~58
Park MS / 2017 / The efficacy of Bifidobacterium longum BORI and Lactobacillus acidophilus ad031 probiotic treatment in infants with rotavirus infection / Nutrients 9:E887
Li Z / 2016 / Anti-obese effects of two lactobacilli and two bifidobacteria on ICR mice fed on a high fat diet / Biochem. Biophys. Res. Commun. 480:222~227
Ku S / 2016 / Review on Bifidobacterium bifidum BGN4: functionality and nutraceutical applications as a probiotic microorganism / Int. J. Mol. Sci. 17:E1544
Shen J / 2012 / The gut microbiota, obesity and insulin resistance / Mol. Aspects Med. 34:39~58
Park MS / 2017 / The efficacy of Bifidobacterium longum BORI and Lactobacillus acidophilus ad031 probiotic treatment in infants with rotavirus infection / Nutrients 9:E887
Li Z / 2016 / Anti-obese effects of two lactobacilli and two bifidobacteria on ICR mice fed on a high fat diet / Biochem. Biophys. Res. Commun. 480:222~227
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