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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 32 - 39 (8page)
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초록· 키워드
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Background/Aims: Endoluminal functional lumen imaging probe (EndoFLIP) is a modality that enables clinicians to measure volume-controlled distension of the esophagus. This study aimed to assess the utility of EndoFLIP in patients who had achalasia treated with peroral endoscopic myotomy (POEM). We hypothesized that improvement in the distensibility index (DI) is correlated with the postoperative clinical outcome of POEM. Methods: Patients who underwent POEM for achalasia at Cha Bundang Medical Center were included. Physiological measurements of the lower esophageal sphincter (LES) pressure before and after POEM were assessed using EndoFLIP. Patients’ symptoms were recorded using the Eckardt score. Results: A total of 52 patients with achalasia were included in this study. Patients with a post-POEM DI below 7 (30 or 40 mL) had a significantly higher rate of incomplete response after POEM (p=0.001). Changes in LES pressure or integrated relaxation pressure after POEM were also significantly associated with an incomplete response (p=0.026 and p=0.016, respectively). Multivariate analysis showed that post-POEM DI <7 was the most important predictor of an incomplete response after POEM (p=0.004). Conclusions: Lower post-POEM DI values were associated with an incomplete post-POEM response. Therefore, post- POEM DI at the esophagogastric junction using EndoFLIP is a useful index for predicting the clinical outcome of POEM in patients with achalasia.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Kim N / 2008 / The prevalence of and risk factors for erosive oesophagitis and non-erosive reflux disease : a nationwide multicentre prospective study in Korea / Aliment Pharmacol Ther 27:173~185
Cho YS / 2005 / Prevalence and clinical spectrum of gastroesophageal reflux : a population-based study in Asan-si, Korea / Am J Gastroenterol 100:747~753
Nam SY / 2009 / Obesity and weight gain as risk factors for erosive oesophagitis in men / Aliment Pharmacol Ther 29:1042~1052
Nam SY / 2010 / Abdominal visceral adipose tissue volume is associated with increased risk of erosive esophagitis in men and women / Gastroenterology 139:1902~1911
Corley DA / 2007 / Abdominal obesity, ethnicity and gastro-oesophageal reflux symptoms / Gut 56:756~762
Cho YS / 2005 / Prevalence and clinical spectrum of gastroesophageal reflux : a population-based study in Asan-si, Korea / Am J Gastroenterol 100:747~753
Nam SY / 2009 / Obesity and weight gain as risk factors for erosive oesophagitis in men / Aliment Pharmacol Ther 29:1042~1052
Nam SY / 2010 / Abdominal visceral adipose tissue volume is associated with increased risk of erosive esophagitis in men and women / Gastroenterology 139:1902~1911
Corley DA / 2007 / Abdominal obesity, ethnicity and gastro-oesophageal reflux symptoms / Gut 56:756~762
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