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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 201 - 210 (10page)
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초록· 키워드
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Biotransformation of ginsenosides by microorganisms alters the absorption and bioavailability of ginseng as a medicinal herb. In this study, we isolated two kinds of fermenting microorganisms from Eoyukjang, which is a traditional Korean fermented food made from soybean. Next, we identified and detected their ability to convert major ginsenosides to compound K. The two microorganisms, referred to as R2-6 and R2- 15, had 100% similarity with Lactobacillus plantarum subsp. plantarum ATCC 14917T and Lactobacillus rhamnosus JCM 1136T, respectively. The optimal pH and growth temperature of the isolates were determined to be pH 6-7 and 30℃. After fermentation for 30 days, the major ginsenosides in the mountain-cultivated ginseng were transformed to the highly bioactive ginsenoside, compound K, in the final product.
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참고문헌 (26)
참고문헌 신청
Choi KT / 2008 / Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng C. A. Meyer / Acta Pharmacol. Sin 29:1109~1118
이상명 / 2015 / Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition / Journal of Ginseng Research 39(4):384~391
Hasegawa H / 2004 / Proof of the mysterious efficacy of ginseng: basic and clinical trials: metabolic activation of ginsenoside: deglycosylation by intestinal bacteria and esterification with fatty acid / J. Pharmacol. Sci 95:153~157
Padmanaban Mohanan / 2018 / Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions / Journal of Ginseng Research 42(2):123~132
이창호 / 2014 / A review on the medicinal potentials of ginseng and ginsenosides on cardiovascular diseases / Journal of Ginseng Research 38(3):161~166
이상명 / 2015 / Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition / Journal of Ginseng Research 39(4):384~391
Hasegawa H / 2004 / Proof of the mysterious efficacy of ginseng: basic and clinical trials: metabolic activation of ginsenoside: deglycosylation by intestinal bacteria and esterification with fatty acid / J. Pharmacol. Sci 95:153~157
Padmanaban Mohanan / 2018 / Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions / Journal of Ginseng Research 42(2):123~132
이창호 / 2014 / A review on the medicinal potentials of ginseng and ginsenosides on cardiovascular diseases / Journal of Ginseng Research 38(3):161~166
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Changes of Ginsenoside Compositions in Cultivated Wild Ginseng with Different Steaming Temperatures and Time
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Complete Biotransformation of Protopanaxatriol-Type Ginsenosides in Panax ginseng Leaf Extract to Aglycon Protopanaxatriol by β-Glycosidases from Dictyoglomus turgidum and Pyrococcus furiosus
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Tracing of chemical transformations of ginsenosides in white, red, and black ginsengs based on UHPLC-Q/TOF-MS
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Induction of Ginsenosides Using Fungal Endophytes Isolated from Mountain-simulated Ginseng
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Biotransformation of Protopanaxadiol- Type Ginsenosides in Korean Ginseng Extract into Food-Available Compound K by an Extracellular Enzyme from Aspergillus niger
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Study on Growth and Ginsenoside Content Changes in 5-6 Year Old GAP-Certified Ginseng from Geumsan
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Bacterial Diversity of a Single Soil Sample of a Ginseng Cultivating Field and Usage of Bacterial Enzymes from Isolates for Ginsenoside Bioconversion
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Quality control of ginseng and its products by determination of ginsenoside using LC-DAD-ELSD
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Simultaneous determination of HPLC/PDA method for the detection and quantification of 33 ginsenosides in red ginseng
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Chryseobacterium panacisoli sp. nov., Isolated from Ginseng Cultivating Soil with Ginsenoside Converting Activity
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Bioconversion Using Lactic Acid Bacteria: Ginsenosides, GABA, and Phenolic Compounds
Journal of Microbiology and Biotechnology
2017 .01
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Inhibitory Effect of Ginsenosides Rh1 and Rg2 on Oxidative Stress in LPS-Stimulated RAW 264.7 Cells
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Ginsenosides analysis in the crude saponin fraction extracted from Korean red ginseng, and its efficacious analysis against acute pulmonary inflammation in mice
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Anti-inflammatory Effects of the Ginsenosides by Regulating Inflammatory Signaling in Macrophages
한국미생물학회 학술대회논문집
2021 .08
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