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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 35 - 45 (11page)
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초록· 키워드
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Purpose: To investigate the influence of donor age on corneal graft survival following primary penetrating keratoplasty(PK) with imported donor corneas. Methods: The eyes of patients who underwent primary PK with imported donor corneas were classified retrospectivelyinto two groups according to a donor-age cutoff of 65 years. Primary outcome measures were rejection-free graft survival and graft survival. Cox proportional hazard regression analysis was used to assessthe factors affecting graft survival. Survival analysis was performed using the Kaplan-Meier method, whiledifferences between groups were examined using a log-rank test. A subgroup analysis of low- and high-riskeyes according to preoperative diagnosis was also performed. Results: A total of 140 eyes from 138 patients (age, 58 ± 18 years) were enrolled. Cox regression analysis revealedthat the donor age of 65 years or older group presented an increased risk of both graft rejection andfailure. Survival analysis revealed that rejection-free graft survival and graft survival rates were higher in eyesin the donor age of less than 65 years group. Finally, in the subgroup analysis, both rejection-free graft survivaland graft survival rates were significantly higher in the donor age of less than 65 years group than in the donorage of 65 years or older group, but only in the low-risk subgroup. Conclusions: Donor age may correlate with graft survival in primary PK performed with imported donor corneas. Donor age could be a considerable factor in primary PK with imported donor corneas, especially in preoperativelylow-risk patients.
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참고문헌 (22)
참고문헌 신청
Williams KA / 1992 / Factors predictive of corneal graft survival. Report from the Australian Corneal Graft Registry / Ophthalmology 99:403~414
Kim MK / 1997 / Long-term outcome of graft rejection after penetrating keratoplasty / J Korean Ophthalmol Soc 38:1553~1560
Krohn J / 2005 / The influence of donor age and cause of death on corneal endothelial cell density / Acta Ophthalmol Scand 83:746~750
Kwon JW / 2016 / Analyses of factors affecting endothelial cell density in an eye bank corneal donor database / Cornea 35:1206~1210
Wagoner MD / 2010 / Outcome of primary adult optical penetrating keratoplasty with imported donor corneas / Int Ophthalmol 30:127~136
Kim MK / 1997 / Long-term outcome of graft rejection after penetrating keratoplasty / J Korean Ophthalmol Soc 38:1553~1560
Krohn J / 2005 / The influence of donor age and cause of death on corneal endothelial cell density / Acta Ophthalmol Scand 83:746~750
Kwon JW / 2016 / Analyses of factors affecting endothelial cell density in an eye bank corneal donor database / Cornea 35:1206~1210
Wagoner MD / 2010 / Outcome of primary adult optical penetrating keratoplasty with imported donor corneas / Int Ophthalmol 30:127~136
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