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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 1,015 - 1,020 (6page)
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초록· 키워드
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Staphylococcus aureus is a representative pathogenic bacterium carefully controlled in the dairy industry because it causes bovine mastitis and thus, can enter the dairy chain. Furthermore, the emergence of multi-drug resistant S. aureus is a big problem. We previously isolated a Lactococcus lactis strain producing a bacteriocin that exhibited strong antimicrobial activity against S. aureus. In this study, we investigated the synergistic inhibition of S. aureus by the bacteriocin and a bacteriophage (SAP84) which is specific to the organism. The bacteriocin (12.5-100 AU/mL) inhibited the growth of S. aureus KCTC 3881 in a dose-dependent manner, as did the bacteriophage SAP84 (0.001-1 MOI; multiplicity of infection). Co-treatment with the bacteriocin (100 AU/mL) and the bacteriophage (0.1 MOI) significantly inhibited the growth of S. aureus compared to each treatment alone (bacteriocin or bacteriophage), indicating the two components showed synergistic inhibition of S. aureus. Therefore, the bacteriocin and bacteriophage combination can be used as a good strategy for controlling pathogenic bacteria.
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등록된 정보가 없습니다.
참고문헌 (12)
참고문헌 신청
정동민 / 2011 / Rapid Concentration of Some Bacteriocin-like Compounds Using an Organic Solvent / Food Science and Biotechnology 20(5):1457~1459
Daeschel MA / 1992 / Food biopreservatives of microbial origin / CRC Press :57~80
Feuerstein R / 2017 / Dynamic interactions between dermal macrophages and Staphylococcus aureus / J Leukoc Biol 101:99~106
Garcia P / 2010 / Synergy between the phage endolysin LysH5 and nisin to kill Staphylococcus aureus in pasteurized milk / Int J Food Microbiol 141:151~155
Gough R / 2017 / A simple method for the purification of nisin / Probiotics Antimicrob Proteins 9:363~369
Daeschel MA / 1992 / Food biopreservatives of microbial origin / CRC Press :57~80
Feuerstein R / 2017 / Dynamic interactions between dermal macrophages and Staphylococcus aureus / J Leukoc Biol 101:99~106
Garcia P / 2010 / Synergy between the phage endolysin LysH5 and nisin to kill Staphylococcus aureus in pasteurized milk / Int J Food Microbiol 141:151~155
Gough R / 2017 / A simple method for the purification of nisin / Probiotics Antimicrob Proteins 9:363~369
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