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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국응용생명화학회 Journal of applied biological chemistry Journal of applied biological chemistry 제58권 제1호
- 발행연도
- 2015.1
- 수록면
- 89 - 95 (7page)
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초록· 키워드
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Helicobacter pylori infection causes gastrointestinal diseases such as chronic gastritis, peptic ulcers, and may lead to gastric cancer. Several studies have reported that lactobacilli present on broccoli show inhibitory activity against H. pylori. Here, we evaluated aqueous broccoli, fermented by Lactobacillus plantarum MG208, for its fermentation characteristics and anti-H. pylori activities including antibacterial activity, growth inhibition, anti-adhesion, and urease inhibition. The results indicated that the fermentation characteristics changed significantly depending on the amount of aqueous broccoli used for fermentation (p <0.05). There was no significant difference between the samples before fermentation (p >0.05). However, a significant concentration-dependent difference was noted in antibacterial activity and urease inhibition (p <0.05) following the addition of aqueous broccoli. Growth inhibition in the 10 mg/mL sample was significantly higher as compared to the negative control and similar to that with amoxicillin (positive control) (p <0.05). Anti-adhesion activity of aqueous broccoli was also significantly different (p <0.05) from the negative control. Therefore, aqueous broccoli fermented by L. plantarum MG208 could prove useful as a functional diet for protection of the gastric environment against H. pylori infection.
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참고문헌 (55)
참고문헌 신청
AOAC / 1984 / In Official methods of analysis / Association of official analytical chemists
Apostolidis E / 2011 / Inhibition of Helicobacter pylori by fermented milk and soymilk using select lactic acid bacteria and link to enrichment of lactic acid and phenolic content / Food Biotechnol 25:58~76
Beil W / 2007 / EPs 7630, an extract from Pelargonium sidoides roots inhibits adherence of Helicobacter pylori to gastric epithelial cells / Phytomedicine 14:5~8
Blaser MJ / 2004 / Helicobacter pylori persistence: biology and disease / J Clin Invest 113:321~333
Canducci F / 2000 / A lyophilized and inactivated culture of Lactobacillus acidophilus increases Helicobacter pylori eradication rates / Aliment Pharmacol Ther 14:1625~1629
Apostolidis E / 2011 / Inhibition of Helicobacter pylori by fermented milk and soymilk using select lactic acid bacteria and link to enrichment of lactic acid and phenolic content / Food Biotechnol 25:58~76
Beil W / 2007 / EPs 7630, an extract from Pelargonium sidoides roots inhibits adherence of Helicobacter pylori to gastric epithelial cells / Phytomedicine 14:5~8
Blaser MJ / 2004 / Helicobacter pylori persistence: biology and disease / J Clin Invest 113:321~333
Canducci F / 2000 / A lyophilized and inactivated culture of Lactobacillus acidophilus increases Helicobacter pylori eradication rates / Aliment Pharmacol Ther 14:1625~1629
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