The Effects of Bronchiectasis on Asthma Exacerbation

Kang, Hye Ran; Choi, Gyu-Sik; Park, Sun Jin; Song, Yoon Kyung; Kim, Jeong Min; Ha, Junghoon; Lee, Yung Hee; Lee, Byoung Hoon; Kim, Sang-Hoon; Lee, Jae Hyung

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자료유형: 학술저널

저자정보: Kang, Hye Ran (Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine) Choi, Gyu-Sik (Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine) Park, Sun Jin (Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine) Song, Yoon Kyung (Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine) Kim, Jeong Min (Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine) Ha, Junghoon (Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine) Lee, Yung Hee (Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine) Lee, Byoung Hoon (Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji) Kim, Sang-Hoon Lee, Jae Hyung

저널정보: 대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제77권 제5호

발행연도: 2014.1

수록면: 209 - 214 (6page)

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Background: Bronchiectasis and asthma are different in many respects, but some patients have both conditions. Studies assessing the effect of bronchiectasis on asthma exacerbation are rare. The aim of this study is to investigate the effect of bronchiectasis on asthma exacerbation. Methods: We enrolled 2,270 asthma patients who were followed up in our hospital. Fifty patients had bronchiectasis and asthma. We selected fifty age- and sex-matched controls from the 2,220 asthma patients without bronchiectasis, and assessed asthma exacerbation and its severity based on the annual incidence of total asthma exacerbation, annual prevalence of steroid use, and frequency of emergency room visits and hospitalizations due to asthma exacerbation in each group. Results: Fifty patients (2.2%) had bronchiectasis and asthma. The annual incidence of asthma exacerbation was higher in patients with asthma and bronchiectasis than in patients with asthma alone ($1.08{\pm}1.68$ vs. $0.35{\pm}0.42$, p=0.004). The annual prevalence of steroid use ($0.9{\pm}1.54$ vs. $0.26{\pm}0.36$, p=0.006) and the frequency of emergency room visits ($0.46{\pm}0.84$ vs. $0.02{\pm}0.13$, p=0.001) due to asthma exacerbation were also higher in patients with asthma and bronchiectasis than in patients with asthma alone. Conclusion: Bronchiectasis is associated with difficult asthma control.

#Bronchiectasis #Asthma #Disease Exacerbation

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