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자료유형
학술저널
저자정보
Qianqian Xue (Qingdao University) Ningning He (Qingdao University) Zhibin Wang (The Affiliated Hospital of Qingdao University) Xiuxiu Fu (The Affiliated Hospital of Qingdao University) Lynn Htet Htet Aung (Qingdao University) Yan Liu (Qingdao University) Min Li (Qingdao University) Jae Youl Cho (Sungkyunkwan University) Yanyan Yang (Qingdao University) Tao Yu (The Affiliated Hospital of Qingdao University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.45 No.1
발행연도
2021.1
수록면
22 - 31 (10page)

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초록· 키워드

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Atherosclerosis (AS) is a leading cause of cardiovascular diseases (CVDs) and it results in a high rate of death worldwide, with an increased prevalence with age despite advances in lifestyle management and drug therapy. Atherosclerosis is a chronic progressive inflammatory process, and it mainly presents with lipid accumulation, foam cell proliferation, inflammatory response, atherosclerotic plaque formation and rupture, thrombosis, and vascular calcification. Therefore, there is a great need for reliable therapeutic drugs or remedies to cure or alleviate atherosclerosis and reduce the societal burden. Ginsenosides are natural steroid glycosides and triterpene saponins obtained mainly from the plant ginseng. Several recent studies have reported that ginsenosides have a variety of pharmacological activities against several diseases including inflammation, cancer and cardiovascular diseases. This review focuses on describing the different pharmacological functions and underlying mechanisms of various active ginsenosides (Rb1,-Rd, -F, -Rg1, -Rg2, and -Rg3, and compound K) for atherosclerosis, which could provide useful insights for developing novel and effective anti-cardiovascular drugs.

목차

ABSTRACT
1. Introduction
2. Ginsenosides and its anti-atherosclerotic activity
3. Discussion
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