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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 182 - 182 (1page)
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Benign prostatic hyperplasia (BPH) is a non-malignant enlargement of the prostate gland, resulted from hyperplastic changes of prostate epithelial and stromal cells and it can be lead to lower urinary tract symptoms. Panicum dichotomiflorum (PD) is an annual grass distributing throughout the world. This study was aimed to evaluate the protective effect of PD extract on benign prostatic hyperplasia (BPH) in a rat model of testosterone-induced BPH. BPH of rat was induced by daily subcutaneous (s.c) administration of testosterone propionate (TP) 3 mg/kg for four weeks. Simultaneously, rats were also administered daily oral gavage of PD (150 mg/kg), finasteride (10 mg/kg) as a positive control or vehicle. After final treatment, all animals were sacrificed humanely and prostates of each animal were isolated, weighed and collected for further analysis. Administration of PD to testosterone-induced BPH rats notably reduced relative prostate ... 전체 초록 보기
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