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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 185 - 185 (1page)
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Epileptic seizure disorders are characterized by unpredictable abnormal electrical discharge, loss of consciousness, and convulsions. 60% of adult patients are Temporal lobe epilepsy(TLE), and 60% of them have hippocampal sclerosis. TLE patients have a poor prognosis and, in particular, when hippocampal sclerosis is accompanied, the cure rate decreases to less than 20%. The pilocarpine rodents model exhibiting hippocampal sclerosis is commonly used in TLE research and has been well known. However, it is difficult to establish a modeling protocol due to the very high mortality rate and the low efficiency with which spontaneous recurrent seizures(SRS) is observed. In this study, we constructed a suitable rodent model for epilepsy studies by our well established protocol using pilocarpine. We used C57BL/6J mice to inject various concentrations of piloca ... 전체 초록 보기
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The correlation of neuronal disorder with the alterations of Phospholipase C (PLC) beta expressionin the hippocampus following pilocarpine-induced status epilepticus
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Dose- and Time-Related Effects of Pilocarpine Mouthwash on Salivation
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Increased expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 after pilocarpineinduced status epilepticus in mice
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Time-course changes of hippocalcin expression in the mouse hippocampus following pilocarpine-induced status epilepticus
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