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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
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- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제25권 제4호
- 발행연도
- 2020.1
- 수록면
- 208 - 216 (9page)
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Parallel with the current pediatric obesity epidemic, the escalating rates of youth-onset type 2 diabetes mellitus (T2DM) have become a major public health burden. Although lifestyle modification can be the first-line prevention for T2DM in youths, there is a lack of evidence to establish optimal specific exercise strategies for obese youths at high risk for T2DM. The purpose of this narrative review is to summarize the potential impact of exercise on 2 key pathophysiological risk factors for T2DM, insulin sensitivity and β-cell function, among obese youths. The studies cited are grouped by use of metabolic tests, i.e., direct and indirect measures of insulin sensitivity and β-cell function. In general, there are an increasing number of studies that demonstrate positive effects of aerobic exercise, resistance exercise, and the 2 combined on insulin sensitivity. However, a lack of evidence exists for the effect of any exercise modality on β-cell functional improvement. We also suggest a future direction for research into exercise medical prevention of youth-onset T2DM. These suggestions focus on the effects of exercise modalities on emerging biomarkers of T2DM risk.
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참고문헌 (83)
참고문헌 신청
Dabelea D / 2014 / Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009 / JAMA 311:1778~1786
Mayer-Davis EJ / 2017 / Incidence trends of type 1 and type 2 diabetes among youths, 2002-2012 / N Engl J Med 377:301
Fazeli Farsani S / 2013 / Global trends in the incidence and prevalence of type 2 diabetes in children and adolescents : a systematic review and evaluation of methodological approaches / Diabetologia 56:1471~1488
Copeland KC / 2013 / Management of newly diagnosed type 2 Diabetes Mellitus(T2DM)in children and adolescents / Pediatrics 131:364~382
Defronzo RA / 2009 / Banting lecture. From the triumvirate to the ominous octet : a new paradigm for the treatment of type 2diabetes mellitus / Diabetes 58:773~795
Mayer-Davis EJ / 2017 / Incidence trends of type 1 and type 2 diabetes among youths, 2002-2012 / N Engl J Med 377:301
Fazeli Farsani S / 2013 / Global trends in the incidence and prevalence of type 2 diabetes in children and adolescents : a systematic review and evaluation of methodological approaches / Diabetologia 56:1471~1488
Copeland KC / 2013 / Management of newly diagnosed type 2 Diabetes Mellitus(T2DM)in children and adolescents / Pediatrics 131:364~382
Defronzo RA / 2009 / Banting lecture. From the triumvirate to the ominous octet : a new paradigm for the treatment of type 2diabetes mellitus / Diabetes 58:773~795
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