지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 11 - 21 (11page)
이용수
초록· 키워드
오류제보하기
Objectives: This study aimed to investigate the efficacy of Ephedra sinica (E. sinica), Panax ginseng (P. ginseng), and Alisma orientale (A. orientale) Extract (MIT) on insulin resistance induced by Non-alcoholic fatty liver disease (NAFLD). Methods: C57BL /6 male mice (8-week-old, 20 g) were divided into four groups: control group (Ctrl), high-fat diet group (HFDF), high fat diet with metformin administration group (METT), and high fat diet with MIT administration group (MITT). Each 10 mice were allocated to each group (a total of 40 mice). All mice were allowed to eat fat-rich diet freely throughout the experiment. To examine the effect of MIT, we observed Cannabinoid receptor type 1 (CB1), Cannabinoid receptor type 2 (CB2), G protein-coupled receptor 55 (GPR55), and Transforming growth factor-β (TGF-β). Results: In the MITT group, positive reactions of the CB1, CB2, and GPR55 were significantly was significantly suppressed compared to the HFDF group. The positive reactions of the CD36 and TGF-β in the liver tissue were significantly suppressed in MITT. Conclusions: MIT has the effect of improving NAFLD induced insulin resistance through the regulation of the lipid metabolism.
목차
등록된 정보가 없습니다.
참고문헌 (48)
참고문헌 신청
Younossi Z / 2018 / Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention / Nat Rev Gastroenterol Hepatol 15(1):11~20
Michelotti GA / 2013 / NAFLD, NASH and liver cancer / Nat Rev Gastroenterol Hepatol 10(11):656~665
Akshintala D / Nonalcoholic Fatty Liver Disease: The Overlooked Complication of Type 2 Diabetes, In Endotext
Li L / 2016 / Obesity is an independent risk factor for non-alcoholic fatty liver disease: evidence from a meta-analysis of 21cohort studies / Obes Rev 17(6):510~519
E.L. Anderson / 2015 / The prevalence of non-alcoholic fatty liver disease in children and adolescents: a systematic review and meta-analysis / PLOS ONE 10:e0140908
Michelotti GA / 2013 / NAFLD, NASH and liver cancer / Nat Rev Gastroenterol Hepatol 10(11):656~665
Akshintala D / Nonalcoholic Fatty Liver Disease: The Overlooked Complication of Type 2 Diabetes, In Endotext
Li L / 2016 / Obesity is an independent risk factor for non-alcoholic fatty liver disease: evidence from a meta-analysis of 21cohort studies / Obes Rev 17(6):510~519
E.L. Anderson / 2015 / The prevalence of non-alcoholic fatty liver disease in children and adolescents: a systematic review and meta-analysis / PLOS ONE 10:e0140908
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
麻黃藥鍼이 비만 유발 생쥐의 지방대사에 미치는 영향
대한한방내과학회지
2016 .01
-
Reply to Letter regarding “The usefulness of metabolic score for insulin resistance for the prediction of incident non-alcoholic fatty liver disease in Korean adults”
Clinical and Molecular Hepatology
2023 .01
-
Letter regarding “The usefulness of metabolic score for insulin resistance for the prediction of incident non-alcoholic fatty liver disease in Korean adults”
Clinical and Molecular Hepatology
2023 .01
-
치자 추출물의 지방대사조절을 통한 비알콜성 지방간 유도 인슐린저항성 개선 효과
동의생리병리학회지
2019 .10
-
치자 추출물의 지방대사조절을 통한 비알콜성 지방간 유도 인슐린저항성 개선 효과
동의생리병리학회지
2019 .01
-
Silkworm attenuates non-alcoholic fatty liver disease in free fatty acid-induced HepG2 hepatocytes and in high fat diet-fed mice
한국실험동물학회 학술발표대회 논문집
2020 .07
-
External electrical stimulation suppresses hepatic lipid accumulation by modulating lipid metabolism in non-alcoholic fatty liver animal models
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Non-alcoholic fatty liver disease: the pathologist’s perspective
Clinical and Molecular Hepatology
2023 .02
-
Comparative study of MCD diet-induced fatty liver of the C57BL/6N mice originated from three different sources
한국실험동물학회 학술발표대회 논문집
2016 .08
-
Effect of Korean Red Ginseng on metabolic syndrome
Journal of Ginseng Research
2021 .05
-
Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease
Clinical and Molecular Hepatology
2023 .02
-
Non-Alcoholic Fatty Liver Disease: The Emerging Burden in Cardiometabolic and Renal Diseases
Diabetes and Metabolism Journal
2017 .01
-
Correspondence on Editorial regarding “Screening and prediction of nonalcoholic fatty liver disease using a peripheral insulin resistance index: Potential benefits and limitations”
Clinical and Molecular Hepatology
2023 .01
-
Effect of Korean Red Ginseng in chronic liver disease
Journal of Ginseng Research
2017 .10
-
A Nomogram for Predicting Non-Alcoholic Fatty Liver Disease in Obese Children
Pediatric Gastroenterology, Hepatology & Nutrition
2020 .01
-
Development of non-alcoholic steatohepatitis mouse model
한국실험동물학회 학술발표대회 논문집
2021 .07
-
The Risk for Insulin Resistance according to the Degree of Non-Alcoholic Fatty Liver Disease in Korean Men
Journal of Korean Medical Science
2016 .01
-
Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective
Endocrinology and Metabolism
2019 .01
-
Endogenous catalase delays high-fat diet-induced liver injury in mice
The Korean Journal of Physiology & Pharmacology
2017 .05
-
Screening strategies for non-alcoholic fatty liver disease: a holistic approach is needed
Clinical and Molecular Hepatology
2023 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0