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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 125 - 138 (14page)
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Ketocarotenoid?biofortifed crops are required as natural additives with respect to their Rubi-like reddish color and strong antioxidative properties for foods and feeds. They can be an alternative means of microalgal and bacterial systems and do not depend on chemical synthesis, providing safe, sustainable, and processing-free platforms. To reach sufcient commercial demands, diferent metabolic engineering strategies have been used in diverse crop plants. In this study, we summarized the current achievements for de novo production of ketocarotenoids in major crops and described host crop-specifc tactics to optimize the ketocarotenoid biosynthetic pathway, considering the following diferent levels and types of carotenoid being accumulated as precursors: lutein and zeaxanthin in maize seeds; lutein in rice seeds, canola seeds, soybean seeds, and tobacco fowers; zeaxanthin in potato tubers; β?carotene in carrot roots; and lycopene in tomato fruits. This study sug?gests prospects for the advanced performance of ketocarotenoid biofortifcation in crops in two crucial points: host crop cultivar and the elaborately designed genetic strategies. The latter includes an increase in the total carotenoid capacity by co-consideration to supply precursors and stabilizers, the prevention of metabolite loss in competing or catabolic pathways or both pathways, and the sensible choice of genes and genetic elements for optimal expression. Furthermore, progresses in synthetic biology and new biotechnology, such as genome editing, could accelerate the development of high-valued “Rubi Crops,” which satisfy the nutritional and functional needs of humans and animals.
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참고문헌 (51)
참고문헌 신청
Mi-Jeong Ahn / 2012 / Production of ketocarotenoids in transgenic carrot plants with an enhanced level of b-carotene / Plant Biotechnology Reports 6(2):133~140
Bai C / 2014 / An in vitro system for the rapid functional characterization of genes involved in carotenoid biosynthesis and accumulation / Plant J 77:464~475
Bai C / 2016 / Bottlenecks in carotenoid biosynthesis and accumulation in rice endosperm are influenced by the precursor–product balance / Plant Biotechnol J 14:195~205
Bai C / 2017 / Reconstruction of the astaxanthin biosynthesis pathway in rice endosperm reveals a metabolic bottleneck at the level of endogenous β-carotene hydroxylase activity / Transgenic Res 26:13~23
Breitenbach J / 2014 / A novel carotenoid, 4-keto-α-carotene, as an unexpected by-product during genetic engineering of carotenogenesis in rice callus / Phytochemistry 98:85~91
Bai C / 2014 / An in vitro system for the rapid functional characterization of genes involved in carotenoid biosynthesis and accumulation / Plant J 77:464~475
Bai C / 2016 / Bottlenecks in carotenoid biosynthesis and accumulation in rice endosperm are influenced by the precursor–product balance / Plant Biotechnol J 14:195~205
Bai C / 2017 / Reconstruction of the astaxanthin biosynthesis pathway in rice endosperm reveals a metabolic bottleneck at the level of endogenous β-carotene hydroxylase activity / Transgenic Res 26:13~23
Breitenbach J / 2014 / A novel carotenoid, 4-keto-α-carotene, as an unexpected by-product during genetic engineering of carotenogenesis in rice callus / Phytochemistry 98:85~91
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