지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 82 - 85 (4page)
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초록· 키워드
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Paradoxical reactions in patients treated with tumor necrosis factor-alpha inhibitors (TNFis) have an estimated prevalence of 1.5% to 5%. Such reactions usually present as psoriasiform eruptions on the trunk and extremities along with palmar and flexural involvement. When affecting the scalp, new-onset psoriasis induced by TNFi can result in non-scarring or scarring alopecia. Although the paradoxical reaction was first reported in 2003, this TNFi-associated psoriatic alopecia (TiAPA) has been recently reported with increasing frequency. This condition is characteristically reversible and requires clinical and histopathological identification from other diseases for proper treatment. The cessation of TNFi therapy may not be mandatory, and decision to continue TNFi therapy depends on the severity of TiAPA and the riskbenefit ratio of treatment modification on the underlying disease. Herein, we report a case of TiAPA in a patient with inflammatory bowel disease whose alopecia improved following suspension of TNFi. We also describe the clinical and histopathological diagnostic criteria based on review of the literature.
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등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Brown G / 2017 / Tumor necrosis factor-α inhibitor-induced psoriasis:systematic review of clinical features, histopathological findings, and management experience / J Am Acad Dermatol 76:334~341
최창환 / 2017 / Second Korean guidelines for the management of ulcerative colitis / Intestinal research 15(1):7~37
Medkour F / 2010 / Development of diffuse psoriasis with alopecia during treatment of Crohn’s disease with infliximab / Gastroenterol Clin Biol 34:140~141
Toda-Brito H / 2015 / Adalimumab-induced psoriatic alopecia/alopecia areata-like reaction in a patient with Crohn's disease / Dermatol Online J 21:13030
Doyle LA / 2011 / Psoriatic alopecia/alopecia areata-like reactions secondary to anti-tumor necrosis factor-α therapy : a novel cause of noncicatricial alopecia / Am J Dermatopathol 33:161~166
최창환 / 2017 / Second Korean guidelines for the management of ulcerative colitis / Intestinal research 15(1):7~37
Medkour F / 2010 / Development of diffuse psoriasis with alopecia during treatment of Crohn’s disease with infliximab / Gastroenterol Clin Biol 34:140~141
Toda-Brito H / 2015 / Adalimumab-induced psoriatic alopecia/alopecia areata-like reaction in a patient with Crohn's disease / Dermatol Online J 21:13030
Doyle LA / 2011 / Psoriatic alopecia/alopecia areata-like reactions secondary to anti-tumor necrosis factor-α therapy : a novel cause of noncicatricial alopecia / Am J Dermatopathol 33:161~166
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