Validation of Korean Version of Low Anterior Resection Syndrome Score Questionnaire

김창우; 정운경; 손경모; 김익용; 박지원; 정승용; 박규주; 이석환

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자료유형: 학술저널

저자정보: 김창우 (경희대학교) 정운경 (계명대학교) 손경모 (부산대학교) 김익용 (연세대학교) 박지원 (서울대학교병원) 정승용 (서울대학교) 박규주 (서울대학교) 이석환 (경희대학교)

저널정보: 대한대장항문학회 Annals of Coloproctology Annals of Coloproctolgy Vol.36 No.2

발행연도: 2020.1

수록면: 83 - 87 (5page)

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연구방법

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Purpose: Patients who undergo radical surgery for rectal cancer often experience low anterior resection syndrome (LARS). Symptoms of this syndrome include frequent bowel movements, gas incontinence, fecal incontinence, fragmentation, and urgency. The aim of this study was to investigate the convergent validity, discriminative validity, and reliability of the Korean version of the LARS score questionnaire. Methods: The English LARS score questionnaire was translated into Korean using the forward-and-back translation method. A total of 146 patients who underwent radical surgery for rectal cancer answered the Korean version of the LARS score questionnaire including an anchor question assessing the impact of bowel function. Participants answered the questionnaire once more after 2 weeks. Results: The Korean LARS score questionnaire showed high convergent validity in terms of high correlation between the LARS score and quality of life (perfect fit 55.5% vs. moderate fit 37.6% vs. no fit 6.8%, respectively; P < 0.001). The LARS score also showed good discriminative validity between groups of patients differing by sex (29 for males vs. 25 for females; P = 0.014), tumor level (29 for ≤8 cm vs. 24 for >8 cm; P = 0.021), and radiotherapy (32 for yes vs. 24 for no; P = 0.001). The LARS score also demonstrated high reliability at test-retest with no difference between scores at the first and second tests (intraclass correlation coefficient: Q1 = 0.932; Q2 = 0.909, Q3 = 0.944, Q4 = 0.931, and Q5 = 0.942; P < 0.001, respectively). Conclusion: The Korean version of the LARS score questionnaire has proven to be a valid and reliable tool for measuring LARS in Korean patients with rectal cancer.

#Low anterior resection syndrome #Rectal cancer #Quality of life #Validation #Questionnaire

참고문헌 (16)

참고문헌 신청

Allemani C / 2018 / Global surveillance of trends in cancer survival 2000-14(CONCORD-3) : analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 populationbased registries in 71 countries / Lancet 391:1023~1075

Emmertsen KJ / 2012 / Low anterior resection syndrome score : development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer / Ann Surg 255:922~928

Bregendahl S / 2013 / Bowel dysfunction after low anterior resection with and without neoadjuvant therapy for rectal cancer : a population-based cross-sectional study / Colorectal Dis 15:1130~1139

Lee WY / 2008 / Surgical autonomic denervation results in altered colonic motility: an explanation for low anterior resection syndrome? / Surgery 143:778~783

Kim KH / 2011 / Effectiveness of biofeedback therapy in the treatment of anterior resection syndrome after rectal cancer surgery / Dis Colon Rectum 54:1107~1113

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김창우

소속기관 경희대학교

주요연구분야 공학 > 재료·에너지공학 > 기타 재료·에너지공학 공학 > 전기전자공학 > 전기공학

논문수 111 이용수 3,983

Woon Kyung Jeong

소속기관 Keimyung University School of Medicine

주요연구분야 의약학 > 기초의학 > 미생물학 자연과학 > 생물학

논문수 30 이용수 103

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소속기관 부산대학교병원