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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 312 - 319 (8page)
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Study Design: Observational study.Purpose: To evaluate healthy volunteers and patients with spinal canal lesions using apparent diffusion coefficient (ADC) maps with diffusion-weighted imaging.Overview of Literature: Decompression surgery for lumbar spinal stenosis (LSS) is selected on the basis of subjective assessment and cross-sectional magnetic resonance imaging (MRI). However, there is no objective standard for this procedure.Methods: We performed 3T MRI in 10 healthy volunteers and 13 patients with LSS. The ADC values in the spinal canal were evaluated at 46 vertebrae (L4/5 and L5/S1 for each participant), and the reduced and conventional fields of view were compared.Results: The ADC values were 2.72±0.12 at L4/5 in healthy volunteers, 2.76±0.19 at L5/S1 in healthy volunteers, 1.77±0.58 at L4/5 in patients with LSS, and 2.35±0.29 at L5/S1 in patients with LSS. The ADC value at L4/5 in patients with LSS was significantly lower than that at L5/S1 in patients with LSS and that at L4/5 and L5/S1 in healthy volunteers (<i>p</i> <0.05). With an ADC cutoff value of 2.46 to identify LSS, this approach provided an area under the curve of 0.81, sensitivity of 0.92, and specificity of 0.76 (<i>p</i> <0.05).Conclusions: Preoperative examination using ADC maps permits visualization and quantification of spinal canal lesions, thus proving the utility of ADC maps in the selection of decompression surgery for LSS.
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참고문헌 (24)
참고문헌 신청
Basser PJ / 2002 / Diffusion-tensor MRI : theory, experimental design and data analysis : a technical review / NMR Biomed 15:456~467
Beaulieu C / 1994 / Determinants of anisotropic water diffusion in nerves / Magn Reson Med 31:394~400
Beaulieu C / 1996 / Changes in water diffusion due to Wallerian degeneration in peripheral nerve / Magn Reson Med 36:627~631
Basser PJ / 1996 / Microstructural and physiological features of tissues elucidated by quantitativediffusion-tensor MRI / J Magn Reson B 111:209~219
Minematsu K / 1992 / Diffusion-weighted magnetic resonance imaging : rapid and quantitative detection of focal brain ischemia / Neurology 42:235~240
Beaulieu C / 1994 / Determinants of anisotropic water diffusion in nerves / Magn Reson Med 31:394~400
Beaulieu C / 1996 / Changes in water diffusion due to Wallerian degeneration in peripheral nerve / Magn Reson Med 36:627~631
Basser PJ / 1996 / Microstructural and physiological features of tissues elucidated by quantitativediffusion-tensor MRI / J Magn Reson B 111:209~219
Minematsu K / 1992 / Diffusion-weighted magnetic resonance imaging : rapid and quantitative detection of focal brain ischemia / Neurology 42:235~240
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