메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Chan Hyung Lee (Seoul National University Bundang Hospital) 윤혁 (Seoul National University Bundang Hospital) Dong Jun Oh (Seoul National University Bundang Hospital) Jae Min Lee (Seoul National University Bundang Hospital) Yoon Jin Choi (Seoul National University Bundang Hospital) Cheol Min Shin (Seoul National University Bundang Hospital) Young Soo Park (Seoul National University Bundang Hospital) Nayoung Kim (Seoul National University Bundang Hospital) Dong Ho Lee (Seoul National University Bundang Hospital) 김주성 (서울대학교)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.18 No.1
발행연도
2020.1
수록면
79 - 84 (6page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background/Aims: Crohn’s disease is associated with altered body composition, such as low muscle mass, which can affect clinical outcomes. However, there are few studies regarding the effect of sarcopenia on prognosis of Crohn’s disease. In this study, we evaluated the body composition at the initial diagnosis of Crohn’s disease and analyzed the clinical meaning of sarcopenia. Methods: We conducted a retrospective review of medical records of patients who were diagnosed as Crohn’s disease and underwent computed tomography within 3 months after diagnosis. Sarcopenia was defined as an L3 skeletal muscle index (SMI) of <49 cm2/m2 for men and <31 cm2/m2 for women. Outcomes such as need for hospitalization, surgery, use of steroids, immunomodulators and biologics were analyzed. Results: A total of 79 patients (male, 73.4%; mean age, 29.9 years) were included and 40 patients (51%) were diagnosed as sarcopenia. C-reactive protein (CRP) level was correlated with sarcopenia (P=0.044). Erythrocyte sedimentation rate (ESR) showed a tendency to decrease inversely with SMI (r=–0.320, P=0.008) and hemoglobin and albumin tended to increase in proportion to SMI (hemoglobin: r=0.271, P=0.016 and albumin: r=0.350, P=0.002). However, there was no statistically significance in time-to-first-event analysis in aspects of sarcopenia. Conclusions: Approximately 50% of patients with newly diagnosed as Crohn’s disease had sarcopenia. CRP levels were higher in the sarcopenia group and SMI correlated with ESR, hemoglobin, and albumin. However, none of prognostic values were demonstrated.

목차

등록된 정보가 없습니다.

참고문헌 (22)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0