지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 질병관리본부 Osong Public Health and Research Persptectives Osong Public Health and Research Persptectives Vol.10 No.1
- 발행연도
- 2019.1
- 수록면
- 6 - 11 (6page)
이용수
초록· 키워드
오류제보하기
Objectives: Despite all the efforts and increased knowledge of rabies, the exact mechanisms of infection and mortality from the rabies virus are not well understood. To understand the mechanisms underlying the pathogenicity of rabies virus infection, it is crucial to study the tissue that the rabies virus naturally infects in humans. Methods: Cerebellum brain tissue from 9 human post mortem cases from Iran, who had been infected with rabies virus, were examined histopathologically and immunohistochemically to evaluate the innate immune responses against the rabies virus. Results: Histopathological examination revealed inflammation of the infected cerebellum and immunohistochemical analyses showed an increased immunoreactivity of heat shock protein 70, interleukin-6, interleukin-1, tumor necrosis factor-alpha, caspase-3, caspase-9, toll-like receptor3 and toll-like receptor4 in the infected brain tissue. Conclusion: These results indicated the involvement of innate immunity in rabies infected human brain tissue, which may aggravate the progression of this deadly disease.
목차
등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
Jackson AC / 2002 / Rabies pathogenesis / J Neurovirol 8(4):267~269
Meltzer MI / 1998 / A review of the economics of the prevention and control of rabies. Part 2: Rabies in dogs, livestock and wildlife / Pharmacoeconomics 14(5):481~498
Martinez L / 2000 / Global infectious disease surveillance / Int J Infect Dis 4(4):222~228
Fu ZF / 1997 / Rabies and rabies research: past, present and future / Vaccine 15(Suppl):S20~S24
Hemachudha T / 2002 / Human rabies : a disease of complex neuropathogenetic mechanisms and diagnostic challenges / Lancet Neurol 1(2):101~109
Meltzer MI / 1998 / A review of the economics of the prevention and control of rabies. Part 2: Rabies in dogs, livestock and wildlife / Pharmacoeconomics 14(5):481~498
Martinez L / 2000 / Global infectious disease surveillance / Int J Infect Dis 4(4):222~228
Fu ZF / 1997 / Rabies and rabies research: past, present and future / Vaccine 15(Suppl):S20~S24
Hemachudha T / 2002 / Human rabies : a disease of complex neuropathogenetic mechanisms and diagnostic challenges / Lancet Neurol 1(2):101~109
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Strategies to maintain Korea’s animal rabies non-occurrence status
Clinical and Experimental Vaccine Research
2018 .01
-
Seroprevalence of rabies virus antibody for dogs and cats in Seoul during 2017?2019
Journal of Biomedical and Translational Research
2021 .01
-
응급의료센터로 내원한 동물교상 환자의 노출 후 공수병 예방치료의 임상적 분석
대한응급의학회지
2018 .08
-
Paralytic rabies mimicking Guillain-Barré syndrome: the dilemma still prevails
Journal of Neurocritical Care
2021 .01
-
Rabies neutralizing antibody titers in Korean dogs and cats intended for overseas travel
Korean Journal of Veterinary Research(대한수의학회지)
2023 .06
-
Detection of immunity in sheep following anti-rabies vaccination
Clinical and Experimental Vaccine Research
2023 .04
-
A case of alopecia areata after rabies vaccination: unreported adverse effect?
Clinical and Experimental Vaccine Research
2024 .04
-
Staphylococcus aureus derived hyaluronic acid and bacillus Calmette-Guerin purified proteins as immune enhancers to rabies vaccine and related immuno-histopathological alterations
Clinical and Experimental Vaccine Research
2021 .09
-
Protection Motivation Theory and Rabies Protective Behaviors Among School Students in Chonburi Province, Thailand
예방의학회지
2021 .11
-
Conservation of matrix protein genes in rabies viruses circulating in South Korea since 1999
Korean Journal of Veterinary Research(대한수의학회지)
2018 .01
-
Indirect ELISA for the Detection of Rabies Virus Antibodies in Dog Sera
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2017 .09
-
Phylogeography of the current rabies viruses in Indonesia
Journal of Veterinary Science
2015 .12
-
Epidemiology of Animal Bites and Factors Associated With Delays in Initiating Post-exposure Prophylaxis for Rabies Prevention Among Animal Bite Cases: A Population-based Study
예방의학회지
2017 .01
-
Epidemiological Features of Human Cases After Bites/Scratches From Rabies-suspected Animals in Zenica-Doboj Canton, Bosnia and Herzegovina
예방의학회지
2019 .01
-
Immunogenicity of an inactivated rabies vaccine for animals derived from the recombinant ERAGS strain
Clinical and Experimental Vaccine Research
2021 .01
-
Comparative evaluation of gold nanoparticles and Alum as immune enhancers against rabies vaccine and related immune reactivity, physiological, and histopathological alterations: in vivo study
Clinical and Experimental Vaccine Research
2023 .01
-
Establishment of multiplex RT-PCR for differentiation between rabies virus with and that without mutation at position 333 of glycoprotein
Journal of Veterinary Science
2020 .03
-
Generation of a recombinant rabies virus expressing green fluorescent protein for a virus neutralization antibody assay
Journal of Veterinary Science
2021 .07
-
Chimeric rabies glycoprotein with a transmembrane domain and cytoplasmic tail from Newcastle disease virus fusion protein incorporates into the Newcastle disease virion at reduced levels
Journal of Veterinary Science
2017 .08
-
Outer membrane proteins of Salmonella Typhimurium as an adjuvant in rabies vaccine
Clinical and Experimental Vaccine Research
2021 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0