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자료유형
학술저널
저자정보
Tabbalat Ramzi A. (Department of Cardiology Abdali Hospital Amman Jordan.) Khader Yousef S. (Department of Community Medicine Jordan University of Science and Technology Irbid Jordan.) Hammoudeh Ayman J (Department of Cardiology Istishari Hospital Amman Jordan.) Alhaddad Imad A. (Department of Cardiology Jordan Hospital Amman Jordan.)
저널정보
아시아심장혈관영상의학회 Cardiovascular Imaging Asia Cardiovascular Imaging Asia Vol.5 No.2
발행연도
2021.1
수록면
37 - 43 (7page)

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Objective Quantification of coronary artery calcium (CAC) has been reported in selected cohorts in USA, Europe, and South America. In the present study, the age- and gender-stratified CAC score (CACS) in a Middle Eastern cohort referred for coronary CT angiography (CCTA) was reported. Materials and Methods Consecutive patients referred for CCTA and CACS were included in the present study. Patients with previous percutaneous coronary intervention, coronary artery bypass grafting, or myocardial infarction were excluded. CACS was determined using the Agatston score in all patients prior to contrast injection. Patients were divided based on gender and then into eight age strata. Results A total of 2564 Middle Eastern patients (37.2% women, 69.6% Jordanians) 19??3 years of age were included in the present study. Men had higher CACS than women (215.4±544.8 vs. 158.1±443.6, p=0.006) and the prevalence and amount of calcium increased steadily with age in both genders. CAC burden significantly increased with every additional modifiable risk factor (hypertension, diabetes mellitus, dyslipidemia, and cigarette smoking); subjects without risk factors had a mean CACS of 83 and subjects with all four risk factors a mean CACS of 359. Conclusion To the best of our knowledge, this is the first report in which CAC burden in a Middle Eastern population referred for CCTA was characterized. Men had higher CACS than women. CAC burden increased with advancing age and with increasing number of modifiable risk factors. Additional studies are necessary to determine the clinical significance of these findings.

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