지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 447 - 452 (6page)
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초록· 키워드
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Purpose: The recent trend in breast cancer treatment is to minimize axillary dissection. However, no pattern of axillary metastasis has been precisely established. The purpose of this study was to evaluate the metastatic lymphatic pattern using near-infrared fluorescence imaging with indocyanine green (ICG) in breast cancer with cytologically proven axillary metastasis. Methods: This was a prospective single-center study. We evaluated 147 patients with breast cancer involving cytologically proven axillary metastasis, and compared physiological and nonphysiological lymphatic metastasis. Results: We performed lymphatic mapping for 64 patients who exhibited level II lymphatic flow on near-infrared fluorescence imaging with ICG, and found that all had axillary metastasis: 51 patients who did not receive neoadjuvant chemotherapy (NAC) and 13 patients post- NAC. Of patients who did not receive NAC, 32 had physiological lymphatic metastasis and 19 had nonphysiological lymphatic metastasis. The risk factors for nonphysiological lymphatic metastasis were age ≥55 years, high Ki-67 index (>20%), and perinodal extension in both univariate and multivariate analysis (p<0.05). Conclusion: Patients with identified risk factors in cytologically- proven axillary metastasis who did not receive NAC may have nonphysiological lymphatic metastasis.
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등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Dewis R / 2009 / Breast Cancer: Diagnosis and Treatment: An Assessment of Need / National Collaborating Centre for Cancer :13~35
Donker M / 2014 / Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial / Lancet Oncol 15:1303~1310
Giuliano AE / 2017 / Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis : the ACOSOG Z0011(Alliance)randomized clinical trial / JAMA 318:918~926
Guo J / 2017 / Comparison of sentinel lymph node biopsy guided by indocyanine green, blue dye, and their combination in breast cancer patients: a prospective cohort study / World J Surg Oncol 15:196
Schaafsma BE / 2011 / The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery / J Surg Oncol 104:323~332
Donker M / 2014 / Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial / Lancet Oncol 15:1303~1310
Giuliano AE / 2017 / Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis : the ACOSOG Z0011(Alliance)randomized clinical trial / JAMA 318:918~926
Guo J / 2017 / Comparison of sentinel lymph node biopsy guided by indocyanine green, blue dye, and their combination in breast cancer patients: a prospective cohort study / World J Surg Oncol 15:196
Schaafsma BE / 2011 / The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery / J Surg Oncol 104:323~332
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