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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objective：The purposes of this study were to compare the working memory span between mild cognitive impairment (MCI) and Alzheimer’s disease (AD) in the Korean elderly population and to evaluate the effectiveness of the working memory span tests. Methods：32 normal controls (NC), 26 patients with MCI and 28 AD patients at a mild stage were participated in this study. We used newly devised working memory span tests (Word span test and Dot matrix) according to the components of working memory ; central executive, phonological loop, and visuospatial sketchpad. And the results were compared with the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet (CERAD-K). To evaluate the effectiveness of the working memory tests and CERAD-K to screen MCI and AD, receiver operating characteristic curves were plotted. Results：All subsets of the two working memory span tests showed significant decline in verbal and visuospatial working memory in AD. But there was no significant difference between NC and MCI. Compared to CERAD-K, the two working memory tests showed good effectiveness to discriminate AD. Conclusion：This study showed that working memory span tests could be effective diagnosing tools for detecting AD. But for the MCI, the working memory impairment was not prominent than episodic memory impairment. This is supposed to result from the various kinds of working memory components, especially the episodic buffer.
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참고문헌 (21)
참고문헌 신청
Fischer P / 2007 / Conversion from subtypes of mild cognitive impairment to Alzheimer dementia / Neurology 68:288~291
Atkinson RC / 1968 / The psychology of learning and motivation. Vol 2 / Academic Press :89~195
Baddeley A / 1992 / Working memory / Science 255:556~559
Baddeley A / 2000 / The episodic buffer: a new component of working memory? / Trends Cogn Sci 4:417~423
Hale JB / 2002 / Analyzing digit span components for assessment of attention processes / J Psychoeduc Assess 20:128~143
Atkinson RC / 1968 / The psychology of learning and motivation. Vol 2 / Academic Press :89~195
Baddeley A / 1992 / Working memory / Science 255:556~559
Baddeley A / 2000 / The episodic buffer: a new component of working memory? / Trends Cogn Sci 4:417~423
Hale JB / 2002 / Analyzing digit span components for assessment of attention processes / J Psychoeduc Assess 20:128~143
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