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자료유형
학술저널
저자정보
Daisuke Kajiwara (Chiba University) Hiroto Kamoda (Chiba Cancer Center) Tsukasa Yonemoto (Chiba Cancer Center) Shintaro Iwata (Chiba Cancer Center) Takeshi Ishii (Chiba Cancer Center) Toshinori Tsukanishi (Tsukuba University) Seiji Ohtori (Chiba University) Masashi Yamazaki (Tsukuba University) Akihiko Okawa (National Hospital Organization Chiba Medical Center)
저널정보
대한척추외과학회 Asian Spine Journal Asian Spine Journal Vol.10 No.3
발행연도
2016.1
수록면
553 - 557 (5page)

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A 43-year-old male patient with C5 giant cell tumor (GCT) underwent tumor resection and anterior bone fusion of C4–C6. The tumor recurred locally 9 months after surgery with the patient complaining of neck and shoulder pain similar to his preoperative symptoms. Denosumab was administered and his pain disappeared after a two-month administration, with a sclerotic rim formation seen at the tumor site on computed tomography. He has been followed for 18 months with no evidence of tumor recurrence. Complete resection is generally recommended, but is not easy for many patients with cervical GCT because of the existence of neurovascular structures. Some patients suffer from recurrence and treatment becomes more difficult. As such, denosumab may be an efficacious option for treatment of recurrent GCT of the cervical spine, although long-term follow-up is required to monitor for presence or absence of recurrence.

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