지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 241 - 247 (7page)
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Objective. To evaluate the prevalence of sleep disturbance in Korean patients with ankylosing spondylitis (AS), and its association with disease activity and depression.
Methods. Forty patients with AS and eighty healthy controls were included in this study. Sleep quality was assessed using the Korean version of Pittsburgh sleep quality index (PSQI). Depression was assessed by the Korean version of Beck depression inventory second edition (BDI-2). Ankylosing spondylitis disease activity score-C-reactive protein (ASDAS-CRP) was used to evaluate disease activity. Patients were dichotomized into a good sleeper group (PSQI≤5) and a poor sleeper group (PSQI＞5).
Results. The mean total PSQI score of patients with AS was 7.23±3.84. It was higher than that of the control subjects. AS patients had higher scores in all of the PSQI components, except for the use of sleep medication. Sixty percent of the AS patients were classified as poor sleepers. The mean BASDAI, ASDAS-CRP, and BDI-2 scores of the poor sleeper group were higher than that of the good sleeper group. Significantly, higher disease activity according to ASDAS-CRP was associated with poor sleep quality and depression. Multiple regression analysis revealed that the duration of morning stiffness and depression were independent risk factors that influenced poor sleep quality.
Conclusion. Sleep disturbances are prevalent amongst Korean patients with AS. Lower quality of sleep is significantly associated with higher disease activity and depression. Therefore, optimal management to improve sleep quality in patients with AS is important.
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참고문헌 (23)
참고문헌 신청
Sieper J / 2006 / Concepts and epidemiology of spondyloarthritis / Best Pract Res Clin Rheumatol 20:401~417
Dougados M / 1991 / The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy / Arthritis Rheum 34:1218~1227
Heiberg T / 2011 / Sleep problems are of higher priority for improvement for patients with ankylosing spondylitis than for patients with other inflammatory arthropathies / Ann Rheum Dis 70:872~873
Hultgren S / 2000 / Sleep disturbances in outpatients with ankylosing spondylitisa questionnaire study with gender implications / Scand J Rheumatol 29:365~369
Hakkou J / 2013 / Sleep disturbance in Moroccan patients with ankylosing spondylitis: prevalence and relationships with disease-specific variables, psychological status and quality of life / Rheumatol Int 33:285~290
Dougados M / 1991 / The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy / Arthritis Rheum 34:1218~1227
Heiberg T / 2011 / Sleep problems are of higher priority for improvement for patients with ankylosing spondylitis than for patients with other inflammatory arthropathies / Ann Rheum Dis 70:872~873
Hultgren S / 2000 / Sleep disturbances in outpatients with ankylosing spondylitisa questionnaire study with gender implications / Scand J Rheumatol 29:365~369
Hakkou J / 2013 / Sleep disturbance in Moroccan patients with ankylosing spondylitis: prevalence and relationships with disease-specific variables, psychological status and quality of life / Rheumatol Int 33:285~290
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