지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Purpose: C-reactive protein (CRP) velocity is value of the CRP level divided by the time after fever start. The aim of this study was to attempt to determine the usefulness of CRP velocity to predict the severity of acute pyelonephritis (APN). Methods: We retrospectively reviewed medical records of patients who visited the emergency department (ED) and were diagnosed with APN for five years. The patients underwent computed tomography (CT) in the ED. The characteristics and laboratory findings compared with the CT group were classified from group I to group V as severity of APN. The patients were grouped according to mild and severe based on the CT groups for comparison of area under the curve. Patients who had fever within 24 hours were extracted and the same analysis was performed. Results: A total of 199 patients were enrolled in our study. The CT groups were classified as follows: group 1 (N=24); group 2 (N=25); group 3 (N=80); group 4 (N=58); group 5 (N=12). Statistically significant differences in laboratory results including CRP, CRP velocity, age, and past history of hypertension were found between mild and severe group. The area under ROC curve of CRP and CRP velocity was 0.888 and 0.841 (p<0.05). For APN patients within 24 hours, AUROC of CRP and CRP velocity were 0.871 and 0.949 (p<0.05). However, AUROC comparison did not show statistically significant differences within CRP and CRP velocity (p=0.1410). Conclusion: In APN patients who had fever within 24 hours, CRP and CRP velocity had predictive value for severity of APN.
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참고문헌 (14)
참고문헌 신청
Pepys MB / 2003 / C-reactive protein : a critical update / J Clin Invest 111:1805~1812
Lee CC / 2012 / Pitfalls in using serum C-reactive protein to predict bacteremia in febrile adults in the ED / Am J Emerg Med 30:562~569
Paran Y / 2009 / C-reactive protein velocity to distinguish febrile bacterial infections from non-bacterial febrile illnesses in the emergency department / Crit Care 13:R50
Nahum E / 2012 / Role of C-reactive protein velocity in the diagnosis of early bacterial infections in children after cardiac surgery / J Intensive Care Med 27:191~196
Justo D / 2009 / C-reactive protein velocity following antibiotics in patients with chronic obstructive pulmonary disease exacerbation and community acquired pneumonia / Eur J Intern Med 20:518~521
Lee CC / 2012 / Pitfalls in using serum C-reactive protein to predict bacteremia in febrile adults in the ED / Am J Emerg Med 30:562~569
Paran Y / 2009 / C-reactive protein velocity to distinguish febrile bacterial infections from non-bacterial febrile illnesses in the emergency department / Crit Care 13:R50
Nahum E / 2012 / Role of C-reactive protein velocity in the diagnosis of early bacterial infections in children after cardiac surgery / J Intensive Care Med 27:191~196
Justo D / 2009 / C-reactive protein velocity following antibiotics in patients with chronic obstructive pulmonary disease exacerbation and community acquired pneumonia / Eur J Intern Med 20:518~521
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