메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Dhananjay Yadav (연세대학교) 김장영 (연세대학교) 이미영 (연세대학교) 류훈 (연세대학교) 허지혜 (연세대학교) 배금석 (연세대학교) 안성복 (연세대학교) 정춘희 (연세대학교) 박종택 (연세대학교) 고상백 (연세대학교)
저널정보
연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제58권 제4호
발행연도
2017.7
수록면
763 - 769 (7page)
DOI
10.3349/ymj.2017.58.4.763

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Purpose: Although γ-glutamyltransferase (GGT) is well known to be associated with metabolic syndrome (MS), prospective data on baseline and longitudinal changes in GGT levels and incident cases of MS are limited. We aimed to examine prospective associationsbetween changes in GGT levels over time, as well as at baseline, and incident MS in Korean adults. Materials and Methods: A total of 2579 Korean adults free of MS were followed up for 2.6 years. Data were collected from 2005?2008 (baseline) and from 2008?2011 (follow-up). Serum GGT levels were determined by enzymatic methods. Results: During follow-up, 558 participants (21.6%) developed MS. A gradual increase in the incidence of MS was observed across GGT quartiles. After adjustment for confounding factors, the odds ratio and 95% confidence interval (CI) for new onset MS, comparingthe highest to the lowest quartiles of baseline GGT, was 2.07 (95% CI: 1.52?2.80). The odds ratio for the highest GGT changes(>4 IU/L increase) in comparison to the lowest GGT changes (<-5 IU/L decrease) was 1.75 (95% CI: 1.32?2.33). Among participantswith baseline GGT concentrations <the median, the odds ratio for incident MS, comparing participants with the highest GGT changes with the lowest GGT changes, was 1.52 (95% CI: 1.01?2.31). Among participants with baseline GGT concentration ≥the median, the corresponding odds ratio was 2.75 (95% CI: 1.84?4.10). Conclusion: High initial GGT concentration and increases in GGT concentration over time should be considered independent predictors of and to have a combined effect on incident MS.

목차

등록된 정보가 없습니다.

참고문헌 (34)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0