지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.7
- 수록면
- 786 - 792 (7page)
- DOI
- 10.3349/ymj.2017.58.4.786
이용수
초록· 키워드
오류제보하기
Purpose: The AdvanSureTM AlloScreen assay is an advanced multiplex test that allows for simultaneous detection of specific IgE (sIgE) against multiple allergens. For precise identification of causative allergens in allergic patients, we compared this new multiplexsIgE assay with the ImmunoCAP assay, which is currently the gold-standard method for sIgE detection.
Materials and Methods: Serum samples from 218 Korean allergic disease patients were used to compare the ImmunoCAP and AlloScreen assays with respect to the following 13 allergens: Dermatophagoides pteronyssinus, Dermatophagoides farinae, cat and dog dander, Alternaria, birch, oak, ragweed, mugwort, rye grass, and food allergens (egg white, cow’s milk, peanuts).
Results: A total of 957 paired tests using the 13 allergens were compared. The total agreement ratio ranged from 0.74 (oak) to 0.97 (Alternaria). With respect to class association analyses, the gamma index ranged from 0.819 (rye grass) to 0.990 (Alternaria). The intra-class correlation coefficients for house dust mites, cat and dog dander, Alternaria, birch, ragweed, egg white, cow’s milk, and peanut sIgE titers were >0.8.
Conclusion: The AlloScreen and ImmunoCAP assays exhibited similar diagnostic performance. However, due to methodological differences between the two systems, careful interpretation of their results is needed in clinical applications.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Bousquet PJ / 2007 / Geographical variation in the prevalence of positive skin tests to environmental aeroallergens in the European Community Respiratory Health Survey I / Allergy 62:301~309
Burney P / 2010 / Prevalence and distribution of sensitization to foods in the European Community Respiratory Health Survey: a EuroPrevall analysis / Allergy 65:1182~1188
Cox L / 2008 / Pearls and pitfalls of allergy diagnostic testing: report from the American College of Allergy, Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specific IgE Test Task Force / Ann Allergy Asthma Immunol 101:580~592
Bernstein IL / 2008 / Allergy diagnostic testing: an updated practice parameter / Ann Allergy Asthma Immunol 100(3 Suppl 3):S1~S148
Bousquet J / 2012 / Practical guide to skin prick tests in allergy to aeroallergens / Allergy 67:18~24
Burney P / 2010 / Prevalence and distribution of sensitization to foods in the European Community Respiratory Health Survey: a EuroPrevall analysis / Allergy 65:1182~1188
Cox L / 2008 / Pearls and pitfalls of allergy diagnostic testing: report from the American College of Allergy, Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specific IgE Test Task Force / Ann Allergy Asthma Immunol 101:580~592
Bernstein IL / 2008 / Allergy diagnostic testing: an updated practice parameter / Ann Allergy Asthma Immunol 100(3 Suppl 3):S1~S148
Bousquet J / 2012 / Practical guide to skin prick tests in allergy to aeroallergens / Allergy 67:18~24
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