지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 75 - 81 (7page)
- DOI
- 10.5145/ACM.2021.24.3.2
이용수
초록· 키워드
오류제보하기
Background: Blood volume is the most important parameter for an optimal blood culture;however, the effect of blood volume on blood culture is not clearly understood from patients withsepsis.
Methods: Blood cultures were obtained from 1,049 patients (≥ 15 years old) who visited theemergency department (ED). Two sets of 20 mL each was collected from each patient, 12 mLof which was transferred to 2 and 10 mL FA Plus (aerobic) bottles (bioMerieux, USA) and theremaining into an FN Plus (anaerobic) bottle. Medical records were reviewed to confirm thediagnosis and clinical significance of the blood culture isolates. The positive rate and time-todetection(TTD) were compared between the 2 and 10 mL groups.
Results: Among the 2,098 sets collected, 612 sets (29.2%) were excluded due to inadequate(either too much or too little) blood volume. The positive rate of clinically significant pathogenswas lower in the 2 mL group (6.1%) than in the 10 mL group (7.5%) (P = 0.003) among the 1,486sets. However, there was no significant difference in the positive rate (11.0% vs. 12.5%, P = 0.152)and TTD (15.7 hours vs. 14.2 hours, P = 0.299) among the 585 (39.4%) patients with sepsis.
Conclusion: The positive rate and TTD were similar between the 2 and 10 mL groups frompatients with sepsis who visited the ED, suggesting a high concentration of bacteremia in thisgroup. Therefore, a smaller blood volume should be carefully considered in patients with sepsis inthe ED.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Clinical and Laboratory Standards Institute (CLSI) / 2007 / Principles and procedures for blood cultures; approved guideline
Lamy B / 2016 / How to optimize the use of blood cultures for the diagnosis of bloodstream infections? A state-of-the art / Front Microbiol 7:697
Ilstrup DM / 1983 / The importance of volume of blood cultured in the detection of bacteremia and fungemia / Diagn Microbiol Infect Dis 1:107~110
Cockerill FR 3rd / 2004 / Optimal testing parameters for blood cultures / Clin Infect Dis 38:1724~1730
Kim SC / 2015 / Effect of blood volume in standard anaerobic blood culture bottles of the BacT/ALERT 3D system used for the detection of pathogens and time to detection / PLoS One 10:e0116728
Lamy B / 2016 / How to optimize the use of blood cultures for the diagnosis of bloodstream infections? A state-of-the art / Front Microbiol 7:697
Ilstrup DM / 1983 / The importance of volume of blood cultured in the detection of bacteremia and fungemia / Diagn Microbiol Infect Dis 1:107~110
Cockerill FR 3rd / 2004 / Optimal testing parameters for blood cultures / Clin Infect Dis 38:1724~1730
Kim SC / 2015 / Effect of blood volume in standard anaerobic blood culture bottles of the BacT/ALERT 3D system used for the detection of pathogens and time to detection / PLoS One 10:e0116728
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