지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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The spatial distribution, innervation, and functional role of the bone-associated skeletal nerves have been previously reported in detail. However, studies examining exercise-induced associations between skeletal nerves and bone metabolism are limited. This review introduces a potential relationship between exercise and the skeletal nerves and discusses how it can contribute to exercise-induced bone anabolism. First, the background and current understanding of nerve fiber types and their functions in the skeleton are provided. Next, the influence of exercise and mechanical loading on the skeletal nervous system is elaborated. Effective synthesis of recent studies could serve as an established baseline for the novel discovery of the effects of exercise on skeletal nerve density and bone anabolic activity in the future. Therefore, this review overviews the existing evidence for the neural control of bone metabolism and the potential positive effects of exercise on the peripheral skeletal nervous system. The influence of exercise training models on the relationships of sensory nerve signals with osteoblast-mediated bone formation and the increased bone volume provides the first insight on the potential importance of exercise training in stimulating positive adaptations in the skeletal nerve-bone interaction and its downstream effect on bone metabolism, thereby highlighting its therapeutic potential in a variety of clinical populations.
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등록된 정보가 없습니다.
참고문헌 (78)
참고문헌 신청
H.M. Frost / 1983 / The skeletal intermediary organization / Metabolic Bone Disease and Related Research 4(5):281~290
Ellen M. Hauge / 2001 / Cancellous Bone Remodeling Occurs in Specialized Compartments Lined by Cells Expressing Osteoblastic Markers / Journal of Bone and Mineral Research 16(9):1575~1582
Hiroki Yokota / 2011 / Mechanical Loading: Bone Remodeling and Cartilage Maintenance / Current Osteoporosis Reports 9(4):237~242
William R. Thompson / 2012 / Mechanical regulation of signaling pathways in bone / Gene 503(2):179~193
Janet Rubin / 2006 / Molecular pathways mediating mechanical signaling in bone / Gene 367:1~16
Ellen M. Hauge / 2001 / Cancellous Bone Remodeling Occurs in Specialized Compartments Lined by Cells Expressing Osteoblastic Markers / Journal of Bone and Mineral Research 16(9):1575~1582
Hiroki Yokota / 2011 / Mechanical Loading: Bone Remodeling and Cartilage Maintenance / Current Osteoporosis Reports 9(4):237~242
William R. Thompson / 2012 / Mechanical regulation of signaling pathways in bone / Gene 503(2):179~193
Janet Rubin / 2006 / Molecular pathways mediating mechanical signaling in bone / Gene 367:1~16
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