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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.6
- 수록면
- 345 - 347 (3page)
- DOI
- 10.14348/molcells.2023.0067
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초록· 키워드
오류제보하기
Tumor microenvironment (TME) is a complex status of various cells, hormones, and metabolites surrounding cancer cells. Understanding the phenomenon of TME seems to be a very effective strategy for conquering cancer cells. Pancreatic cancer is a highly lethal malignancy with no current therapeutic options. Lee et al. report a novel metabolic pathway for survival of pancreatic cancer using a metabolite trancing experiment. This distinct pathway provides a new paradigm in the field of cancer therapy using tumor energy metabolism. OAT, ornithine aminotransferase; ODC, ornithine decarboxylase; SRM, spermidine synthase; SMS, spermine synthase; KLF6, Krüppel-like factor 6.
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