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논문 기본 정보

자료유형
학술저널
저자정보
Liqi Shu (Department of Neurology Brown University Providence RI USA) Adam de Havenon (Department of Neurology Yale University New Haven CT USA) Ava L. Liberman (Department of Neurology Weill Cornell Medical Center New York NY USA) Nils Henninger (Department of Neurology University of Massachusetts Worcester MA USA) Eric Goldstein (Department of Neurology Brown University Providence RI USA) Michael E. Reznik (Department of Neurology Brown University Providence RI USA) Ali Mahta (Department of Neurology Brown University Providence RI USA) Fawaz Al-Mufti (Department of Neurology Westchester Medical Center Valhalla NY USA) Jennifer Frontera (Department of Neurology New York University New York NY USA) Karen Furie (Department of Neurology Brown University Providence RI USA) Shadi Yaghi (Department of Neurology Brown University Providence RI USA)
저널정보
대한뇌졸중학회 대한뇌졸중학회지 대한뇌졸중영문학회지 제25권 제1호
발행연도
2023.1
수록면
151 - 159 (9page)

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Background and Purpose Venous thromboembolism (VTE) is a life-threatening complication of stroke. We evaluated nationwide rates and risk factors for hospital readmissions with VTE after an intracerebral hemorrhage (ICH) or acute ischemic stroke (AIS) hospitalization. Methods Using the Healthcare Cost and Utilization Project (HCUP) Nationwide Readmission Database, we included patients with a principal discharge diagnosis of ICH or AIS from 2016 to 2019. Patients who had VTE diagnosis or history of VTE during the index admission were excluded. We performed Cox regression models to determine factors associated with VTE readmission, compared rates between AIS and ICH and developed post-stroke VTE risk score. We estimated VTE readmission rates per day over a 90-day time window post-discharge using linear splines. Results Of the total 1,459,865 patients with stroke, readmission with VTE as the principal diagnosis within 90 days occurred in 0.26% (3,407/1,330,584) AIS and 0.65% (843/129,281) ICH patients. The rate of VTE readmission decreased within first 4–6 weeks (P<0.001). In AIS, cancer, obesity, higher National Institutes of Health Stroke Scale (NIHSS) score, longer hospital stay, home or rehabilitation disposition, and absence of atrial fibrillation were associated with VTE readmission. In ICH, longer hospital stay and rehabilitation disposition were associated with VTE readmission. The VTE rate was higher in ICH compared to AIS (adjusted hazard ratio 2.86, 95% confidence interval 1.93–4.25, P<0.001). Conclusions After stroke, VTE readmission risk is highest within the first 4–6 weeks and nearly three-fold higher after ICH vs. AIS. VTE risk is linked to decreased mobility and hypercoagulability. Studies are needed to test short-term VTE prophylaxis beyond hospitalization in high-risk patients.

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