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자료유형
학술저널
저자정보
Alharbi Reham A. (Department of Pharmaceutical Care King Faisal Specialist Hospital and Research Center Jeddah Saudi Arabia) Aldardeer Namareq F. (Department of Pharmaceutical Care King Faisal Specialist Hospital and Research Center Jeddah Saudi Arabia) Heaphy Emily L. G. (Department of Research King Faisal Specialist Hospital and Research Center Jeddah Saudi Arabia) Alabbasi Ahmad H. (Nahdi Medical Company Medina Saudi Arabia) Albuqami Amjad M. (United Pharmacy Jeddah Saudi Arabia) Hawa Hassan (Department of Critical Care Medicine King Faisal Specialist Hospital and Research Center Jeddah Saudi Arabia)
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care 제38권 제2호
발행연도
2023.5
수록면
209 - 216 (8page)
DOI
10.4266/acc.2022.01550

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Background Percent fluid overload greater than 5% is associated with increased mortality. The appropriate time for fluid deresuscitation depends on the patient's radiological and clinical findings. This study aimed to assess the applicability of percent fluid overload calculations for evaluating the need for fluid deresuscitation in critically ill patients. Methods This was a single-center, prospective, observational study of critically ill adult patients requiring intravenous fluid administration. The study's primary outcome was median percent fluid accumulation on the day of fluid deresuscitation or intensive care unit (ICU) discharge, whichever came first. Results A total of 388 patients was screened between August 1, 2021, and April 30, 2022. Of these, 100 with a mean age of 59.8±16.2 years were included for analysis. The mean Acute Physiology and Chronic Health Evaluation (APACHE) II score was 15.4±8.0. Sixty-one patients (61.0%) required fluid deresuscitation during their ICU stay, while 39 (39.0%) did not. Median percent fluid accumulation on the day of deresuscitation or ICU discharge was 4.5% (interquartile range [IQR], 1.7%–9.1%) and 5.2% (IQR, 2.9%–7.7%) in patients requiring deresuscitation and those who did not, respectively. Hospital mortality occurred in 25 (40.9%) of patients with deresuscitation and six (15.3%) patients who did not require it (P=0.007). Conclusions The percent fluid accumulation on the day of fluid deresuscitation or ICU discharge was not statistically different between patients who required fluid deresuscitation and those who did not. A larger sample size is needed to confirm these findings.

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