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논문 기본 정보

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학술저널
저자정보
Priscila Matovelle (Department of Geriatrics, San Juan de Dios Hospital, Zaragoza, Spain) Bárbara Oliván-Blázquez (Group B21-20R, Health Research Institute of Aragon (IISA), Zaragoza, Spain) Irene Fraile-Peñaranda (Department of Preventive Medicine Unit, Lozano Blesa University Clinical Hospital, Zaragoza, Spain) Alberto Turón-Lanuza (Department of Applied Economics, Zaragoza University, Zaragoza, Spain) Alba Gallego-Royo (Aragonese Healthcare Service (SALUD), Zaragoza, Spain) Verónica Casado-Vicente (Family and Community Medicine, University Health Centre Parquesol, Valladolid, Spain) Rosa Magallón-Botaya (Department of Medicine, Psychiatry and Dermatology, Faculty of Medicine, University of Zaragoza, Zaragoza, Spain)
저널정보
대한노인병학회 Annals of geriatric medicine and research Annals of geriatric medicine and research Vol.28 No.1
발행연도
2024.3
수록면
36 - 45 (10page)
DOI
10.4235/agmr.23.0137

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Background: Challenges of polypharmacy and the impact of coronavirus disease 2019 (COVID-19) pandemic in older patients require further investigation. This retrospective study analyzed the progression of polypharmacy and anticholinergic burden in older patients in a primary care setting before, during, and after the COVID-19 pandemic. Methods: This 3-year cross-sectional study (2019, 2020, and 2021) comprised a dynamic cohort of individuals aged ≥75 years, who attended the Arrabal Primary Care Center in Zaragoza, Spain. Older patients with polypharmacy (≥5 medications) were identified according to their electronic health records. We collected demographic and clinical data, including medication prescriptions, diagnoses, and anticholinergic risks, and performed descriptive and statistical analyses. Results: This study included a total of 1,928 patients with a mean age of 83.52±0.30 years. Over the 3-year study period, the mean number of medications prescribed increased, from 9.4 in 2019 to 10.4 in 2021. The prevalence of excessive polypharmacy (≥10 medications) increased from 39% in 2019 to 45% in 2021. The most commonly prescribed drugs were anilides, proton pump inhibitors, benzodiazepine derivatives, and platelet aggregation inhibitors. Women had a higher prevalence of illnesses and anticholinergic drug prescriptions than men. Conclusion: The results of this study highlighted an upward trend in polypharmacy and excessive polypharmacy among older patients in primary care settings. Future research should focus on optimizing medication management and deprescribing strategies and minimizing the adverse effects of polypharmacy in this population.

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