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논문 기본 정보

자료유형
학술저널
저자정보
Seon Nyo Kim (Sungkyunkwan University) Seung Hyun Kim (Sungkyunkwan University) Chan Kim (Sungkyunkwan University) Hanna Kim (Sungkyunkwan University) Jieun Hwang (Sungkyunkwan University) Misun Yang (Sungkyunkwan University) So Yoon Ahn (Sungkyunkwan University) Se In Sung (Sungkyunkwan University) Yun Sil Chang (Sungkyunkwan University) Hyeseon Kim (Sungkyunkwan University)
저널정보
대한신생아학회 Neonatal medicine Neonatal medicine 제31권 제2호
발행연도
2024.5
수록면
17 - 23 (7page)

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초록· 키워드

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Purpose: To investigate the risk factors associated with hypospadias in ver y low birth weight (VLBW) infants (VLBW Is). Methods: We retrospectively analyzed 729 infants born at ≥24 weeks of gestational age and weighing <1,500 g from Januar y 2012 to December 2022. We assessed the prevalence of hypospadias by birth weight percentiles and also compared the demo­ graphics and placental histopatholog y of the infants with hypospadias (n=52) and those without hypospadias (n=677). Results: Of the 729 patients analysed, hypospadias was recorded in 26 (20.3%), 14 (26.9%), and 12 (2.5%) infants in the <3rd, ≥3rd–<10 t h, a nd ≥10 t h–<90th percentiles, respectively. Of all of the patients with hypospadias, 50% had birth weights <3rd percentile (P<0.001). The hypospadias group demonstrated a longer mean gestational age (30.1 weeks vs. 27.9 weeks, P<0.001), lower incidence of maternal pregnancy­induced hypertension (48.1% vs. 17.3%, P<0.001), lower incidence of pre­ mature rupture of membrane (11.5% vs. 27.1%, P=0.013), lower acute chorioamniotic maternal response (9.1% vs. 35.2%, P<0.001), and higher maternal underperfusion (95.5% vs. 71.9%, P<0.001). Conclusion: The frequency of hypospadias was found to be the highest among VBLW Is <3rd percentile, who were severely small for their gestational age (SGA). Additionally, the incidence increased with a decreasing birth weight. Physical examination is necessar y at birth for VLBW Is classified as SGA. Moreover, the data on the incidence of hypospadias among VLBW Is in neonatal intensive care units can assist in tracking counseling from the prenatal to the postnatal period for patients born <3rd percentile.

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