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논문 기본 정보

자료유형
학술저널
저자정보
Ryoo Seungeun (Division of Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea.) Choi Miyoung (Division of Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea.) Choi Nam-Kyong (Department of Health Convergence, College of Science and Industry Convergence, Ewha Womans University, Seoul, Korea.) Shin Hyoung-Shik (Department of Infectious Diseases, Daejeon Eulji Medical Center, Eulji University, Daejeon, Korea.) Woo Jun Hee (National Academy of Medicine of Korea, Seoul, Republic of Korea) Park Byung-Joo (National Academy of Medicine of Korea, Seoul, Republic of Korea) Oh Sanghoon (Department of Psychiatry, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea)
저널정보
질병관리본부 Osong Public Health and Research Persptectives Osong Public Health and Research Perspectives Vol.15 No.2
발행연도
2024.4
수록면
107 - 114 (8page)
DOI
10.24171/j.phrp.2023.0325

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초록· 키워드

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This systematic review evaluated psychiatric adverse events (AEs) following vaccination against coronavirus disease 2019 (COVID-19). We included studies that reported or investigated psychiatric AEs in individuals who had received an approved COVID-19 vaccine in the Republic of Korea. Systematic electronic searches of Ovid-Medline, Embase, CENTRAL, and KoreaMed databases were conducted on March 22, 2023. Risk of bias was assessed using the Risk of Bias Assessment Tool for Non-randomized Studies 2.0. The study protocol was registered in the International Prospective Register of Systematic Reviews (CRD42023449422). Of the 301 articles initially selected, 7 were included in the final analysis. All studies reported on sleep disturbances, and 2 highlighted anxiety-related AEs. Sleep disorders like insomnia and narcolepsy were the most prevalent AEs, while depression was not reported. Our review suggests that these AEs may have been influenced by biological mechanisms as well as the broader psychosocial context of the COVID-19 pandemic. Although this study had limitations, such as a primary focus on the BNT162b2 vaccine and an observational study design, it offered a systematic, multi-vaccine analysis that fills a critical gap in the existing literature. This review underscores the need for continued surveillance of psychiatric AEs and guides future research to investigate underlying mechanisms, identify risk factors, and inform clinical management.

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