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논문 기본 정보

자료유형
학술저널
저자정보
Adam A. Dmytriw (Neurovascular Centre, Departments of Medical Imaging & Neurosurgery, St. Michael’s Hospital, University of Toronto, Toronto, Canada) Jerry Ku (2Neurovascular Centre, Departments of Medical Imaging & Surgery, Sunnybrook Health Sciences Centre and St. Michael’s Hospital, University of Toronto, Toronto ON, Canada) Ahmed Y. Azzam (Nested Knowledge, Department of Neuroradiology, Mayo Clinic, Rochester MN, USA) Osman Elamin (Nested Knowledge, Department of Neuroradiology, Mayo Clinic, Rochester MN, USA) Nicole Cancelliere (Neurovascular Centre, Departments of Medical Imaging & Surgery, Sunnybrook Health Sciences Centre and St. Michael’s Hospital, University of Toronto, Toronto ON, Canada) Anish Kapadia (Neurovascular Centre, Departments of Medical Imaging & Surgery, Sunnybrook Health Sciences Centre and St. Michael’s Hospital, University of Toronto, Toronto ON, Canada) James D. Rabinov (Neuroendovascular Program, Massachusetts General Hospital & Brigham and Women’s Hospital, Harvard Medical School, Boston MA, USA) Christopher J. Stapleton (Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA) Robert W. Regenhardt (Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA) Pereira Vitor Mendes (Neurovascular Centre, Departments of Medical Imaging & Neurosurgery, St. Michael’s Hospital, University of Toronto, Toronto, Canada) Patel Aman B. (Neuroendovascular Program, Massachusetts General Hospital & Brigham and Women’s Hospital, Harvard Medical School, Boston, USA) Victor X.D. Yang (Neurovascular Centre, Departments of Medical Imaging & Surgery, Sunnybrook Health Sciences Centre and St. Michael’s Hospital, University of Toronto, Toronto ON, Canada)
저널정보
대한뇌혈관외과학회 Journal of Cerebrovascular and Endovascular Neurosurgery Journal of Cerebrovascular and Endovascular Neurosurgery Vol.26 No.2
발행연도
2024.7
수록면
152 - 162 (11page)
DOI
10.7461/jcen.2023.E2023.03.002

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초록· 키워드

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Objective: Stroke is the second-leading cause of death globally. Intracranial atherosclerotic stenosis (ICAS) represents 10-15% of ischemic strokes in Western countries and up to 47% in Asian countries. Patients with ICAS have an especially high risk of stroke recurrence. The aim of this meta-analysis is to reassess recurrent stroke, transient ischemic attack (TIA), and other outcomes with stenting versus best medical management for symptomatic ICAS.Methods: The search protocol was developed a priori according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The OVID Medline, Embase, Web of Science, and Cochrane Library databases were searched from inception to August 14th, 2022.Results: This Meta-analysis Included Four Randomized Controlled Trials (Rcts), With A Total Number Of 991 Patients. The Mean Age Of Participants Was 57 Years. The Total Number Of Intracranial Stenting Patients Was 495, And The Number Of Medical Treatment Patients Was 496. The Included Studies Were Published Between 2011 And 2022. Two Studies Were Conducted In The Usa, And The Other Two In China. All Included Studies Compared Intracranial Stenting To Medical Treatment For Icas.Conclusions: In patients with ischemic stroke due to symptomatic severe intracranial atherosclerosis, the rate of 30-day ischemic stroke, 30-day intracerebral hemorrhage, one-year stroke in territory or mortality favored the medical treatment alone without intracranial stenting. The risk of same-territory stroke at last follow-up, disabling stroke at last follow-up, and mortality did not significantly favor either group. Intracranial stenting for atherosclerosis did not result in significant benefit over medical treatment.

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