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(Iowa State University) (Iowa State University) (Ames High School) (Iowa State University) (Chonbuk National University) (Iowa State University)
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한국생물공학회 한국생물공학회 학술대회 2014 한국생물공학회 춘계학술발표대회 및 국제심포지엄
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    Adult Hippocampal Progenitor Cells (AHPCs) are generally maintained as a dispersed monolayer population of multipotent neural progenitors. To better understand cell-cell interactions among neural progenitors and their influences on cellular characteristics, we generated free-floating cellular aggregates, or neurospheres, from the adherent monolayer population of AHPCs. Cell proliferation, phenotypic differentiation and migrational activities of both AHPC populations (neurospheres and adherent) were examined and compared in vitro, or in vivo following transplantation. Our results from in vitro analyses demonstrate that AHPCs in neurospheres favored differentiation along a glial l ... 전체 초록 보기

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