메뉴 건너뛰기
소속 기관 / 학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
고객센터 ENG
주제분류

피인용 0

검색

    초록·키워드

    Antigenicity of Hantann virus(ROK84-105) and Seoul virus(80-39) harvested from suckling rats brains was better than the viruses grown in Vero E6 cell cultures in S.D. rats, and antigen titers were 40,960 units/ml by ELISA. Infectivity of Hantaan and Seoul virus was completely inactivated with 0.05% formalin at 4℃ for 10 days. The vaccine was made by the modified method of Japanese encephalitis mice brain vaccine and antigen titers of the inactivated purified vaccines was 20,480 units/ml by ELISA. Protein content of the vaccine was 27-50μl/ml. Primary and secondary antibody responses were demonstrated in rats after administration of 512 and 128 units of antigen IM, respectively. Vaccinated Apodemus mice were completely immune after challenge with 1,000 SM LD₅₀ of live ... 전체 초록 보기

    최근 본 자료 전체보기